| Datum | Home | Away | Resultat | Liga |
|---|---|---|---|---|
| 21.11.2021 |  Los Angeles Chargers |  Pittsburgh Steelers | 41 - 37 | NFL |
| 18.11.2021 |  Atlanta Falcons |  New England Patriots | 0 - 25 | NFL |
| 15.11.2021 |  Las Vegas Raiders |  Kansas City Chiefs | 14 - 41 | NFL |
| 15.11.2021 |  San Francisco 49ers |  Los Angeles Rams | 31 - 10 | NFL |
| 14.11.2021 |  Green Bay Packers |  Seattle Seahawks | 17 - 0 | NFL |
| 14.11.2021 |  Denver Broncos |  Philadelphia Eagles | 13 - 30 | NFL |
| 14.11.2021 | Los Angeles Chargers |  Minnesota Vikings | 20 - 27 | NFL |
| 14.11.2021 |  Arizona Cardinals |  Carolina Panthers | 10 - 34 | NFL |
| 14.11.2021 |  Washington Commanders |  Tampa Bay Buccaneers | 29 - 19 | NFL |
| 14.11.2021 |  Tennessee Titans |  New Orleans Saints | 23 - 21 | NFL |
| 14.11.2021 | Pittsburgh Steelers |  Detroit Lions | 16 - 16 | NFL |
| 14.11.2021 |  New York Jets |  Buffalo Bills | 17 - 45 | NFL |
| 14.11.2021 | New England Patriots |  Cleveland Browns | 45 - 7 | NFL |
| 14.11.2021 |  Indianapolis Colts |  Jacksonville Jaguars | 23 - 17 | NFL |
| 14.11.2021 |  Dallas Cowboys | Atlanta Falcons | 43 - 3 | NFL |
| 11.11.2021 |  Miami Dolphins |  Baltimore Ravens | 22 - 10 | NFL |
| 08.11.2021 | Pittsburgh Steelers |  Chicago Bears | 29 - 27 | NFL |
| 07.11.2021 | San Francisco 49ers | Arizona Cardinals | 17 - 31 | NFL |
| 07.11.2021 | Kansas City Chiefs | Green Bay Packers | 13 - 7 | NFL |
| 07.11.2021 | Philadelphia Eagles | Los Angeles Chargers | 24 - 27 | NFL |
| 07.11.2021 |  New York Giants | Las Vegas Raiders | 23 - 16 | NFL |
| 07.11.2021 | New Orleans Saints | Atlanta Falcons | 25 - 27 | NFL |
| 07.11.2021 | Miami Dolphins |  Houston Texans | 17 - 9 | NFL |
| 07.11.2021 | Jacksonville Jaguars | Buffalo Bills | 9 - 6 | NFL |
| 07.11.2021 | Dallas Cowboys | Denver Broncos | 16 - 30 | NFL |
| 07.11.2021 |  Cincinnati Bengals | Cleveland Browns | 16 - 41 | NFL |
| 07.11.2021 | Carolina Panthers | New England Patriots | 6 - 24 | NFL |
| 07.11.2021 | Baltimore Ravens | Minnesota Vikings | 34 - 31 | NFL |
| 07.11.2021 | Los Angeles Rams | Tennessee Titans | 16 - 28 | NFL |
| 04.11.2021 | Indianapolis Colts | New York Jets | 45 - 30 | NFL |
| 01.11.2021 | Kansas City Chiefs | New York Giants | 20 - 17 | NFL |
| 31.10.2021 | New Orleans Saints | Tampa Bay Buccaneers | 36 - 27 | NFL |
| 31.10.2021 | Denver Broncos | Washington Commanders | 17 - 10 | NFL |
| 31.10.2021 | Seattle Seahawks | Jacksonville Jaguars | 31 - 7 | NFL |
| 31.10.2021 | Los Angeles Chargers | New England Patriots | 24 - 27 | NFL |
| 31.10.2021 | New York Jets | Cincinnati Bengals | 34 - 31 | NFL |
| 31.10.2021 | Indianapolis Colts | Tennessee Titans | 31 - 34 | NFL |
| 31.10.2021 | Houston Texans | Los Angeles Rams | 22 - 38 | NFL |
| 31.10.2021 | Detroit Lions | Philadelphia Eagles | 6 - 44 | NFL |
| 31.10.2021 | Cleveland Browns | Pittsburgh Steelers | 10 - 15 | NFL |
| 31.10.2021 | Chicago Bears | San Francisco 49ers | 22 - 33 | NFL |
| 31.10.2021 | Buffalo Bills | Miami Dolphins | 26 - 11 | NFL |
| 31.10.2021 | Atlanta Falcons | Carolina Panthers | 13 - 19 | NFL |
| 31.10.2021 | Minnesota Vikings | Dallas Cowboys | 16 - 20 | NFL |
| 30.10.2021 |  Schweiz |  Russland | 9 - 36 | European Championship |
| 28.10.2021 | Arizona Cardinals | Green Bay Packers | 21 - 24 | NFL |
| 25.10.2021 | Seattle Seahawks | New Orleans Saints | 10 - 13 | NFL |
| 24.10.2021 | Tampa Bay Buccaneers | Chicago Bears | 38 - 3 | NFL |
| 24.10.2021 | Arizona Cardinals | Houston Texans | 31 - 5 | NFL |
| 24.10.2021 | Las Vegas Raiders | Philadelphia Eagles | 33 - 22 | NFL |
