| Datum | Home | Away | Resultat | Liga |
|---|---|---|---|---|
| 28.08.2021 |  Wroclaw Panthers |  Berlin Thunder | 35 - 12 | ELF |
| 28.08.2021 |  Barcelona Dragons |  Frankfurt Galaxy | 14 - 22 | ELF |
| 28.08.2021 |  Zofingen Cheetahs |  Schaffhausen Sharks | 0 - 63 | NLC |
| 28.08.2021 |  Glarus Orks |  Langenthal Invaders | 13 - 48 | NLC |
| 28.08.2021 |  Emmen Dragons |  Zurich State Spartans | 36 - 13 | NLC |
| 28.08.2021 |  Winterthur Warriors |  Bern Grizzlies | 0 - 17 | NLA |
| 28.08.2021 | Winterthur Warriors | Bern Grizzlies | 18 - 46 | U19 Elite |
| 28.08.2021 | Winterthur Warriors |  Basel Gladiators | 22 - 20 | U16 |
| 22.08.2021 |  Thun Tigers |  Bienna Jets | 28 - 19 | NLB |
| 22.08.2021 | Berlin Thunder | Barcelona Dragons | 19 - 3 | ELF |
| 22.08.2021 |  Hamburg Sea Devils | Wroclaw Panthers | 24 - 30 | ELF |
| 22.08.2021 |  Luzern Lions |  St. Gallen Bears | 6 - 13 | NLB |
| 22.08.2021 |  Geneva Whoppers |  Fribourg Cardinals | 6 - 2 | NLB |
| 22.08.2021 | Schaffhausen Sharks | Zurich State Spartans | 25 - 0 | NLC |
| 22.08.2021 | Basel Gladiators | Winterthur Warriors | 13 - 46 | NLA |
| 22.08.2021 |  Zurich Renegades |  Geneva Seahawks | 6 - 0 | U19 Elite |
| 22.08.2021 | Zurich Renegades |  Calanda Broncos | 12 - 20 | U16 |
| 22.08.2021 | Basel Gladiators | Winterthur Warriors | 37 - 16 | U16 |
| 22.08.2021 | Thun Tigers | Bern Grizzlies | 41 - 14 | U19 Elite |
| 21.08.2021 | Zofingen Cheetahs | Langenthal Invaders | 0 - 70 | NLC |
| 21.08.2021 | Calanda Broncos | Bern Grizzlies | 35 - 10 | NLA |
| 21.08.2021 |  Lugano Rebels |  Argovia Pirates | 6 - 25 | NLB |
| 21.08.2021 |  Cologne Centurions |  Leipzig Kings | 24 - 42 | ELF |
| 21.08.2021 | Lugano Rebels |  Riviera Saints | 0 - 33 | U19 Challenge League |
| 15.08.2021 |  Stuttgart Surge | Barcelona Dragons | 12 - 30 | ELF |
| 15.08.2021 | Wroclaw Panthers | Frankfurt Galaxy | 7 - 36 | ELF |
| 15.08.2021 |  Niederbipp Ducks | Zofingen Cheetahs | 37 - 0 | NLC |
| 15.08.2021 |  Neuchatel Knights | Zurich State Spartans | 7 - 6 | NLC |
| 15.08.2021 |  Morges Bandits | Glarus Orks | 30 - 16 | NLC |
| 15.08.2021 |  LUCAF Owls | Emmen Dragons | 29 - 18 | NLC |
| 15.08.2021 | Thun Tigers | Bern Grizzlies | 50 - 12 | U16 |
| 15.08.2021 | Bienna Jets | Geneva Whoppers | 50 - 0 | NLB |
| 15.08.2021 | Zurich Renegades | Basel Gladiators | 48 - 8 | U16 |
| 15.08.2021 | Bienna Jets | Basel Gladiators | 14 - 46 | U19 Elite |
| 14.08.2021 | Argovia Pirates | Luzern Lions | 18 - 3 | NLB |
| 14.08.2021 | Argovia Pirates | Luzern Lions | 28 - 8 | U19 Challenge League |
| 14.08.2021 | Winterthur Warriors | Calanda Broncos | 12 - 23 | U19 Elite |
| 14.08.2021 | Berlin Thunder | Hamburg Sea Devils | 20 - 28 | ELF |
| 14.08.2021 | Winterthur Warriors | Calanda Broncos | 8 - 36 | U16 |
| 08.08.2021 | Leipzig Kings | Stuttgart Surge | 49 - 23 | ELF |
| 08.08.2021 | Frankfurt Galaxy | Hamburg Sea Devils | 35 - 9 | ELF |
| 07.08.2021 | Barcelona Dragons | Cologne Centurions | 60 - 51 | ELF |
| 07.08.2021 | Langenthal Invaders | Morges Bandits | 50 - 20 | NLC |
| 01.08.2021 | Frankfurt Galaxy | Stuttgart Surge | 57 - 3 | ELF |
| 01.08.2021 | Leipzig Kings | Berlin Thunder | 37 - 24 | ELF |
| 01.08.2021 | Cologne Centurions | Wroclaw Panthers | 33 - 31 | ELF |
| 31.07.2021 | Niederbipp Ducks | Neuchatel Knights | 0 - 34 | NLC |
| 31.07.2021 | Hamburg Sea Devils | Barcelona Dragons | 22 - 17 | ELF |
| 25.07.2021 | Stuttgart Surge | Cologne Centurions | 23 - 39 | ELF |
| 25.07.2021 | Niederbipp Ducks | Morges Bandits | 0 - 28 | NLC |
