| 2022-03-26 14:30:0026.03.2022 | Winterthur Warriors | 14 – 6 | Argovia Pirates | U19 Elite | N/A | 1 |
| 2022-03-26 15:00:0026.03.2022 | LUCAF Owls | 0 – 32 | Lugano Rebels | NLC | N/A | 1 |
| 2022-03-26 18:00:0026.03.2022 | Winterthur Warriors | 6 – 34 | Bern Grizzlies | NLA | N/A | 1 |
| 2022-03-27 11:00:0027.03.2022 | Geneva Seahawks | 30 – 12 | Bern Grizzlies | U19 Elite | N/A | 1 |
| 2022-03-27 14:00:0027.03.2022 | Morges Bandits | 28 – 20 | Orks | NLC | N/A | 1 |
| 2022-03-27 14:00:0027.03.2022 | Neuchatel Knights | 3 – 14 | Zurich State Spartans | NLC | N/A | 1 |
| 2022-03-27 14:00:0027.03.2022 | Niederbipp Ducks | 6 – 53 | Dragons | NLC | N/A | 1 |
| 2022-03-27 14:00:0027.03.2022 | Schaffhausen Sharks | 3 – 0 | Langenthal Invaders | NLC | N/A | 1 |
| 2022-03-27 14:30:0027.03.2022 | Geneva Seahawks | 13 – 0 | Zurich Renegades | NLA | N/A | 1 |
| 2022-04-02 14:00:2002.04.2022 | Black Panthers | 12 – 6 | Las Rozas Black Demons | CEFL | N/A | – |
| 2022-04-03 11:00:0003.04.2022 | Calanda Broncos | 59 – 22 | Basel Gladiators | U19 Elite | N/A | 2 |
| 2022-04-03 14:00:0003.04.2022 | Zurich State Spartans | 10 – 8 | Langenthal Invaders | NLC | N/A | 2 |
| 2022-04-03 14:30:0003.04.2022 | Calanda Broncos | 49 – 21 | Thun Tigers | NLA | N/A | 2 |
| 2022-04-10 11:00:0010.04.2022 | Basel Gladiators | 35 – 44 | Argovia Pirates | U19 Elite | N/A | 3 |
| 2022-04-10 11:00:0010.04.2022 | Bern Grizzlies | 8 – 25 | Zurich Renegades | U19 Elite | N/A | 3 |
| 2022-04-10 11:00:0010.04.2022 | St. Gallen Bears | 7 – 44 | Geneva Seahawks | U19 Elite | N/A | 3 |
| 2022-04-10 11:00:0010.04.2022 | Thun Tigers | 48 – 8 | Winterthur Warriors | U19 Elite | N/A | 3 |
| 2022-04-10 11:00:0010.04.2022 | Luzern Lions | 18 – 22 | Bienna Jets | U19 Challenge League | N/A | 3 |
| 2022-04-10 14:00:0010.04.2022 | Luzern Lions | 33 – 13 | Bienna Jets | NLB | N/A | 3 |
| 2022-04-10 14:00:0010.04.2022 | Dragons | 50 – 0 | Zofingen Cheetahs | NLC | N/A | 3 |
| 2022-04-10 14:00:0010.04.2022 | Niederbipp Ducks | 0 – 24 | Neuchatel Knights | NLC | N/A | 3 |
| 2022-04-10 14:30:0010.04.2022 | Bern Grizzlies | 27 – 0 | Geneva Seahawks | NLA | N/A | 3 |
| 2022-04-10 14:30:0010.04.2022 | Thun Tigers | 35 – 20 | Winterthur Warriors | NLA | N/A | 3 |
| 2022-04-10 14:30:0010.04.2022 | Basel Gladiators | 15 – 34 | Calanda Broncos | NLA | N/A | 3 |
| 2022-04-10 14:30:0010.04.2022 | St. Gallen Bears | 17 – 0 | Fribourg Cardinals | NLB | N/A | 3 |
| 2022-04-16 14:30:0016.04.2022 | Basel Gladiators | 14 – 30 | Geneva Seahawks | U19 Elite | N/A | 4 |
| 2022-04-16 18:00:0016.04.2022 | Basel Gladiators | 3 – 31 | Bern Grizzlies | NLA | N/A | 4 |
| 2022-04-16 18:00:0016.04.2022 | Langenthal Invaders | 46 – 7 | Neuchatel Knights | NLC | N/A | 4 |
| 2022-04-16 18:00:0016.04.2022 | LUCAF Owls | 7 – 0 | Orks | NLC | N/A | 4 |
| 2022-04-16 18:00:0016.04.2022 | Zofingen Cheetahs | 0 – 56 | Schaffhausen Sharks | NLC | N/A | 4 |
| 2022-04-17 14:00:0017.04.2022 | Fribourg Cardinals | 21 – 33 | Geneva Whoppers | NLB | N/A | 4 |
| 2022-04-17 14:00:0017.04.2022 | Morges Bandits | 47 – 6 | Niederbipp Ducks | NLC | N/A | 4 |
| 2022-04-18 11:00:0018.04.2022 | Calanda Broncos | 57 – 12 | Winterthur Warriors | U19 Elite | N/A | 4 |
| 2022-04-18 11:00:0018.04.2022 | St. Gallen Bears | 7 – 60 | Zurich Renegades | U19 Elite | N/A | 4 |
| 2022-04-18 11:00:0018.04.2022 | Thun Tigers | 52 – 7 | Argovia Pirates | U19 Elite | N/A | 4 |
| 2022-04-18 14:00:0018.04.2022 | Bienna Jets | 12 – 22 | Argovia Pirates | NLB | N/A | 4 |
| 2022-04-18 14:30:0018.04.2022 | Calanda Broncos | 34 – 6 | Winterthur Warriors | NLA | N/A | 4 |
| 2022-04-18 14:30:0018.04.2022 | Thun Tigers | 34 – 0 | Zurich Renegades | NLA | N/A | 4 |
| 2022-04-18 14:30:0018.04.2022 | St. Gallen Bears | 6 – 5 | Luzern Lions | NLB | N/A | 4 |
| 2022-04-23 00:00:0023.04.2022 | Belgrade SBB Vukovi | 21 – 35 | Vienna Danube Dragons | CEFL | N/A | – |
| 2022-04-23 00:00:0023.04.2022 | Towers | 25 – 56 | Örebro Black Knights | CEFL | N/A | – |
| 2022-04-23 00:00:0023.04.2022 | Dracs | 7 – 49 | Flash de La Courneuve | CEFL | N/A | – |
| 2022-04-23 00:00:0023.04.2022 | Budapest Wolves | 00:00:000:00 | Spartans | CEFL | N/A | – |
| 2022-04-23 14:30:0023.04.2022 | Zurich State Spartans | 14:30:00Abgesagt | Zofingen Cheetahs | NLC | N/A | 5 |
| 2022-04-23 18:00:0023.04.2022 | Langenthal Invaders | 67 – 6 | Niederbipp Ducks | NLC | N/A | 5 |
| 2022-04-23 18:00:0023.04.2022 | Neuchatel Knights | 12 – 5 | LUCAF Owls | NLC | N/A | 5 |
| 2022-04-24 11:00:0024.04.2022 | Bern Grizzlies | 18 – 20 | Winterthur Warriors | U19 Elite | N/A | 5 |
| 2022-04-24 11:00:0024.04.2022 | Geneva Seahawks | 36 – 22 | Zurich Renegades | U19 Elite | N/A | 5 |
| 2022-04-24 11:00:0024.04.2022 | St. Gallen Bears | 0 – 53 | Calanda Broncos | U19 Elite | N/A | 5 |
| 2022-04-24 11:00:0024.04.2022 | Lugano Rebels | 21 – 07 | Neuchatel Knights | U19 Challenge League | N/A | 5 |
| 2022-04-24 14:00:0024.04.2022 | Geneva Whoppers | 07 – 42 | Luzern Lions | NLB | N/A | 5 |
| 2022-04-24 14:00:0024.04.2022 | Dragons | 26 – 06 | Orks | NLC | N/A | 5 |
| 2022-04-24 14:00:0024.04.2022 | Lugano Rebels | 21 – 40 | Schaffhausen Sharks | NLC | N/A | 5 |
| 2022-04-24 14:30:0024.04.2022 | Bern Grizzlies | 24 – 7 | Thun Tigers | NLA | N/A | 5 |
| 2022-04-24 14:30:0024.04.2022 | Geneva Seahawks | 0 – 21 | Calanda Broncos | NLA | N/A | 5 |
| 2022-04-24 14:30:0024.04.2022 | St. Gallen Bears | 28 – 7 | Bienna Jets | NLB | N/A | 5 |
| 2022-04-30 13:00:0030.04.2022 | Bienna Jets | 13:00:00TBD | Lugano Rebels | U19 Challenge League | N/A | 6 |
| 2022-04-30 14:30:0030.04.2022 | Argovia Pirates | 14 – 36 | Geneva Seahawks | U19 Elite | N/A | 6 |
| 2022-04-30 14:30:0030.04.2022 | Winterthur Warriors | 12 – 39 | Basel Gladiators | U19 Elite | N/A | 6 |
| 2022-04-30 14:30:0030.04.2022 | Zurich State Spartans | 7 – 13 | Dragons | NLC | N/A | 6 |
| 2022-04-30 18:00:0030.04.2022 | Winterthur Warriors | 22 – 14 | Zurich Renegades | NLA | N/A | 6 |
| 2022-04-30 18:00:0030.04.2022 | Argovia Pirates | 7 – 3 | Fribourg Cardinals | NLB | N/A | 6 |
| 2022-05-01 11:00:0001.05.2022 | Bern Grizzlies | 33 – 12 | St. Gallen Bears | U19 Elite | N/A | 6 |
| 2022-05-01 11:00:0001.05.2022 | Thun Tigers | 39 – 43 | Calanda Broncos | U19 Elite | N/A | 6 |
| 2022-05-01 12:00:0001.05.2022 | Morges Bandits | 0 – 56 | Luzern Lions | U19 Challenge League | N/A | 6 |
| 2022-05-01 14:00:0001.05.2022 | Orks | 0 – 35 | Schaffhausen Sharks | NLC | N/A | 6 |
| 2022-05-01 14:00:0001.05.2022 | Morges Bandits | 21 – 35 | Langenthal Invaders | NLC | N/A | 6 |
| 2022-05-01 14:00:0001.05.2022 | Zofingen Cheetahs | 0 – 61 | Lugano Rebels | NLC | N/A | 6 |
| 2022-05-01 14:30:0001.05.2022 | Bern Grizzlies | 27 – 20 | Calanda Broncos | NLA | N/A | 6 |
| 2022-05-01 14:30:0001.05.2022 | Thun Tigers | 41 – 6 | Geneva Seahawks | NLA | N/A | 6 |
| 2022-05-07 00:00:0007.05.2022 | Schwäbisch Hall Unicorns | 58 – 7 | Örebro Black Knights | CEFL | N/A | – |
| 2022-05-07 14:00:0007.05.2022 | Neuchatel Knights | 0 – 41 | Bienna Jets | U19 Challenge League | N/A | 7 |
| 2022-05-07 14:30:0007.05.2022 | Calanda Broncos | 36 – 0 | Bern Grizzlies | U19 Elite | N/A | 7 |
| 2022-05-07 14:30:0007.05.2022 | St. Gallen Bears | 6 – 58 | Thun Tigers | U19 Elite | N/A | 7 |
| 2022-05-07 14:30:0007.05.2022 | St. Gallen Bears | 34 – 0 | Geneva Whoppers | NLB | N/A | 7 |
| 2022-05-07 18:00:0007.05.2022 | Calanda Broncos | 35 – 6 | Basel Gladiators | NLA | N/A | 7 |
| 2022-05-08 11:00:0008.05.2022 | Zurich Renegades | 20 – 27 | Basel Gladiators | U19 Elite | N/A | 7 |
| 2022-05-08 11:00:0008.05.2022 | Luzern Lions | 22 – 0 | Lugano Rebels | U19 Challenge League | N/A | 7 |
| 2022-05-08 12:00:0008.05.2022 | Geneva Seahawks | 50 – 0 | Winterthur Warriors | U19 Elite | N/A | 7 |
| 2022-05-08 14:00:0008.05.2022 | Fribourg Cardinals | 8 – 23 | Bienna Jets | NLB | N/A | 7 |
| 2022-05-08 14:00:0008.05.2022 | Luzern Lions | 9 – 14 | Argovia Pirates | NLB | N/A | 7 |
| 2022-05-08 14:00:0008.05.2022 | Dragons | 22 – 12 | Lugano Rebels | NLC | N/A | 7 |
| 2022-05-08 14:00:0008.05.2022 | Schaffhausen Sharks | 9 – 0 | Neuchatel Knights | NLC | N/A | 7 |
| 2022-05-08 14:00:0008.05.2022 | Zofingen Cheetahs | 6 – 28 | Niederbipp Ducks | NLC | N/A | 7 |
| 2022-05-08 14:30:0008.05.2022 | Zurich Renegades | 19 – 62 | Thun Tigers | NLA | N/A | 7 |
| 2022-05-08 15:30:0008.05.2022 | Geneva Seahawks | 21 – 7 | Winterthur Warriors | NLA | N/A | 7 |
| 2022-05-14 14:30:0014.05.2022 | Argovia Pirates | 15 – 0 | Bern Grizzlies | U19 Elite | N/A | 8 |
| 2022-05-14 15:00:0014.05.2022 | E-R Parma Panthers | 21 – 10 | Vienna Danube Dragons | CEFL | N/A | – |
| 2022-05-14 18:00:0014.05.2022 | Argovia Pirates | 15 – 27 | St. Gallen Bears | NLB | N/A | 8 |
| 2022-05-14 18:00:0014.05.2022 | Orks | 7 – 24 | Lugano Rebels | NLC | N/A | 8 |
| 2022-05-14 18:00:0014.05.2022 | Niederbipp Ducks | 14 – 15 | LUCAF Owls | NLC | N/A | 8 |
| 2022-05-14 18:00:0014.05.2022 | Black Panthers | 27 – 45 | Flash de La Courneuve | CEFL | N/A | – |
| 2022-05-14 18:00:0014.05.2022 | Calanda Broncos | 35 – 28 | Budapest Wolves | CEFL | N/A | – |
| 2022-05-15 11:00:0015.05.2022 | Zurich Renegades | 24 – 33 | Thun Tigers | U19 Elite | N/A | 8 |
| 2022-05-15 11:00:0015.05.2022 | Neuchatel Knights | 11:00:0011:00 | Morges Bandits | U19 Challenge League | N/A | 8 |
| 2022-05-15 14:00:0015.05.2022 | Geneva Whoppers | 18 – 25 | Bienna Jets | NLB | N/A | 8 |
| 2022-05-15 14:00:0015.05.2022 | Luzern Lions | 21 – 0 | Fribourg Cardinals | NLB | N/A | 8 |
| 2022-05-15 14:00:0015.05.2022 | Neuchatel Knights | 40 – 23 | Morges Bandits | NLC | N/A | 8 |
| 2022-05-15 14:00:0015.05.2022 | Schaffhausen Sharks | 17 – 03 | Zurich State Spartans | NLC | N/A | 8 |
| 2022-05-15 14:00:0015.05.2022 | Zofingen Cheetahs | 0 – 50 | Langenthal Invaders | NLC | N/A | 8 |
| 2022-05-15 14:30:0015.05.2022 | Zurich Renegades | 0 – 40 | Basel Gladiators | NLA | N/A | 8 |
| 2022-05-21 14:30:0021.05.2022 | Basel Gladiators | 52 – 7 | St. Gallen Bears | U19 Elite | N/A | 9 |
| 2022-05-21 15:00:0021.05.2022 | LUCAF Owls | 0 – 32 | Schaffhausen Sharks | NLC | N/A | 9 |
| 2022-05-21 18:00:0021.05.2022 | Basel Gladiators | 24 – 7 | Geneva Seahawks | NLA | N/A | 9 |
| 2022-05-22 11:00:0022.05.2022 | Bern Grizzlies | 6 – 41 | Thun Tigers | U19 Elite | N/A | 9 |
| 2022-05-22 11:00:0022.05.2022 | Zurich Renegades | 23 – 15 | Calanda Broncos | U19 Elite | N/A | 9 |
| 2022-05-22 11:00:0022.05.2022 | Lugano Rebels | 11:00:0011:00 | Morges Bandits | U19 Challenge League | N/A | 9 |
| 2022-05-22 11:00:0022.05.2022 | Neuchatel Knights | 0 – 14 | Luzern Lions | U19 Challenge League | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Bienna Jets | 7 – 28 | Luzern Lions | NLB | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Fribourg Cardinals | 6 – 12 | St. Gallen Bears | NLB | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Geneva Whoppers | 12 – 23 | Argovia Pirates | NLB | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Lugano Rebels | 22 – 25 | Morges Bandits | NLC | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Neuchatel Knights | 15 – 22 | Dragons | NLC | N/A | 9 |
| 2022-05-22 14:00:0022.05.2022 | Niederbipp Ducks | 21 – 35 | Zurich State Spartans | NLC | N/A | 9 |
| 2022-05-22 14:30:0022.05.2022 | Bern Grizzlies | 69 – 7 | Winterthur Warriors | NLA | N/A | 9 |
| 2022-05-22 14:30:0022.05.2022 | Zurich Renegades | 20 – 44 | Calanda Broncos | NLA | N/A | 9 |
| 2022-05-28 14:00:0028.05.2022 | St. Gallen Bears | 28 – 7 | Argovia Pirates | NLB | N/A | 10 |
| 2022-05-28 14:30:0028.05.2022 | Calanda Broncos | 47 – 26 | Geneva Seahawks | U19 Elite | N/A | 10 |
| 2022-05-28 14:30:0028.05.2022 | Thun Tigers | 42 – 21 | Basel Gladiators | U19 Elite | N/A | 10 |
| 2022-05-28 14:30:0028.05.2022 | Winterthur Warriors | 34 – 14 | St. Gallen Bears | U19 Elite | N/A | 10 |
| 2022-05-28 15:00:0028.05.2022 | Bienna Jets | 15:00:00Abgesagt | Morges Bandits | U19 Challenge League | N/A | 5 |
| 2022-05-28 18:00:0028.05.2022 | Calanda Broncos | 21 – 14 | Geneva Seahawks | NLA | N/A | 10 |
| 2022-05-28 18:00:0028.05.2022 | Thun Tigers | 20 – 24 | Basel Gladiators | NLA | N/A | 10 |
| 2022-05-28 18:00:0028.05.2022 | Langenthal Invaders | 55 – 7 | Orks | NLC | N/A | 10 |
| 2022-05-29 11:00:0029.05.2022 | Zurich Renegades | 33 – 8 | Argovia Pirates | U19 Elite | N/A | 10 |
| 2022-05-29 14:00:0029.05.2022 | Fribourg Cardinals | 12 – 20 | Luzern Lions | NLB | N/A | 10 |
| 2022-05-29 14:00:0029.05.2022 | Lugano Rebels | 62 – 0 | Niederbipp Ducks | NLC | N/A | 10 |
| 2022-05-29 14:00:0029.05.2022 | Morges Bandits | 53 – 6 | Zofingen Cheetahs | NLC | N/A | 10 |
| 2022-05-29 14:30:0029.05.2022 | Zurich Renegades | 12 – 38 | Winterthur Warriors | NLA | N/A | 10 |
| 2022-05-29 14:30:0029.05.2022 | Zurich State Spartans | 6 – 13 | LUCAF Owls | NLC | N/A | 10 |
| 2022-06-04 00:00:0004.06.2022 | Bye Week | 00:00:000:00 | Spielplan | U19 Challenge League | N/A | 11 |
| 2022-06-04 14:30:0004.06.2022 | Argovia Pirates | 12 – 44 | Calanda Broncos | U19 Elite | N/A | 11 |
| 2022-06-04 14:30:0004.06.2022 | Basel Gladiators | 27 – 8 | Bern Grizzlies | U19 Elite | N/A | 11 |
| 2022-06-04 14:30:0004.06.2022 | Geneva Seahawks | 32 – 44 | Thun Tigers | U19 Elite | N/A | 11 |
| 2022-06-04 14:30:0004.06.2022 | Winterthur Warriors | 26 – 43 | Zurich Renegades | U19 Elite | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Geneva Seahawks | 0 – 55 | Bern Grizzlies | NLA | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Winterthur Warriors | 21 – 24 | Thun Tigers | NLA | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Basel Gladiators | 28 – 15 | Zurich Renegades | NLA | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Argovia Pirates | 10 – 42 | Bienna Jets | NLB | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Geneva Whoppers | 0 – 6 | Fribourg Cardinals | NLB | N/A | 11 |
| 2022-06-04 18:00:0004.06.2022 | Cologne Centurions | 40 – 38 | Rams | ELF | N/A | 11 |
| 2022-06-04 18:00:0904.06.2022 | Calanda Broncos | 9 – 21 | E-R Parma Panthers | CEFL | N/A | – |
| 2022-06-05 14:00:0005.06.2022 | LUCAF Owls | 14:00:00Abgesagt | Zofingen Cheetahs | NLC | N/A | 11 |
| 2022-06-05 14:00:0005.06.2022 | Lugano Rebels | 48 – 23 | Zurich State Spartans | NLC | N/A | 11 |
| 2022-06-05 14:00:0005.06.2022 | Morges Bandits | 0 – 13 | Dragons | NLC | N/A | 11 |
| 2022-06-05 14:00:0005.06.2022 | Neuchatel Knights | 16 – 19 | Orks | NLC | N/A | 11 |
| 2022-06-05 15:00:0005.06.2022 | Frankfurt Galaxy | 26 – 29 | Rhein Fire | ELF | N/A | 11 |
| 2022-06-05 15:00:0005.06.2022 | Stuttgart Surge | 9 – 38 | Barcelona Dragons | ELF | N/A | 11 |
| 2022-06-05 15:00:0005.06.2022 | Wroclaw Panthers | 34 – 27 | Leipzig Kings | ELF | N/A | 11 |
| 2022-06-05 15:00:0005.06.2022 | Hamburg Sea Devils | 43 – 18 | Berlin Thunder | ELF | N/A | 11 |
| 2022-06-05 15:00:0005.06.2022 | Raiders | 23 – 29 | Vikings | ELF | N/A | 11 |
| 2022-06-11 00:00:0011.06.2022 | Spielplan | 00:00:000:00 | | U19 Challenge League | N/A | 12 |
| 2022-06-11 14:30:0011.06.2022 | Argovia Pirates | 8 – 23 | St. Gallen Bears | U19 Elite | N/A | 12 |
| 2022-06-11 15:00:0011.06.2022 | Cologne Centurions | 49 – 46 | Raiders | ELF | N/A | 12 |
| 2022-06-11 15:00:0011.06.2022 | Berlin Thunder | 41 – 7 | Rams | ELF | N/A | 12 |
| 2022-06-11 18:00:0011.06.2022 | Calanda Broncos | 23 – 30 | Bern Grizzlies | NLA | N/A | 12 |
| 2022-06-11 18:00:0011.06.2022 | Winterthur Warriors | 13 – 21 | Basel Gladiators | NLA | N/A | 12 |
| 2022-06-11 18:00:0011.06.2022 | Dragons | 20 – 24 | Langenthal Invaders | NLC | N/A | 12 |
| 2022-06-11 18:00:0011.06.2022 | Orks | 19 – 12 | Zurich State Spartans | NLC | N/A | 12 |
| 2022-06-11 18:00:0011.06.2022 | Niederbipp Ducks | 3 – 35 | Schaffhausen Sharks | NLC | N/A | 12 |
| 2022-06-12 11:00:1412.06.2022 | Luzern Lions | 32 – 0 | Lugano Rebels | U19 Challenge League | N/A | 12 |
| 2022-06-12 11:00:1812.06.2022 | Bienna Jets | 39 – 6 | Neuchatel Knights | U19 Challenge League | N/A | 12 |
| 2022-06-12 14:00:0012.06.2022 | Bienna Jets | 7 – 10 | St. Gallen Bears | NLB | N/A | 12 |
| 2022-06-12 14:00:0012.06.2022 | Fribourg Cardinals | 6 – 21 | Argovia Pirates | NLB | N/A | 12 |
| 2022-06-12 14:00:0012.06.2022 | Luzern Lions | 23 – 8 | Geneva Whoppers | NLB | N/A | 12 |
| 2022-06-12 14:00:0012.06.2022 | Leipzig Kings | 17 – 28 | Rhein Fire | ELF | N/A | 12 |
| 2022-06-12 14:00:0012.06.2022 | LUCAF Owls | 0 – 50 | Morges Bandits | NLC | N/A | 12 |
| 2022-06-12 14:30:0012.06.2022 | Zurich Renegades | 37 – 6 | Geneva Seahawks | NLA | N/A | 12 |
| 2022-06-12 15:00:0012.06.2022 | Stuttgart Surge | 25 – 28 | Wroclaw Panthers | ELF | N/A | 12 |
| 2022-06-12 15:00:0012.06.2022 | Hamburg Sea Devils | 21 – 24 | Barcelona Dragons | ELF | N/A | 12 |
| 2022-06-12 15:00:0012.06.2022 | Vikings | 30 – 10 | Frankfurt Galaxy | ELF | N/A | 12 |
| 2022-06-18 14:00:0018.06.2022 | Orks | 50 – 0 | Zofingen Cheetahs | NLC | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Geneva Seahawks | 3 – 14 | Basel Gladiators | NLA | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Winterthur Warriors | 27 – 28 | Calanda Broncos | NLA | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Argovia Pirates | 0 – 21 | Luzern Lions | NLB | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Leipzig Kings | 0 – 14 | Hamburg Sea Devils | ELF | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Barcelona Dragons | 34 – 32 | Cologne Centurions | ELF | N/A | 13 |
| 2022-06-18 18:00:0018.06.2022 | Langenthal Invaders | 28 – 19 | LUCAF Owls | NLC | N/A | 13 |
| 2022-06-19 11:00:2519.06.2022 | Bienna Jets | 20 – 12 | Luzern Lions | U19 Challenge League | N/A | 13 |
| 2022-06-19 11:00:3219.06.2022 | Thun Tigers | 52 – 8 | Geneva Seahawks | U19 Elite | N/A | 13 |
| 2022-06-19 14:00:0019.06.2022 | Thun Tigers | 6 – 36 | Bern Grizzlies | NLA | N/A | 13 |
| 2022-06-19 14:00:0019.06.2022 | Geneva Whoppers | 0 – 29 | St. Gallen Bears | NLB | N/A | 13 |
| 2022-06-19 14:00:0019.06.2022 | Lugano Rebels | 21 – 7 | Neuchatel Knights | NLC | N/A | 13 |
| 2022-06-19 14:00:0019.06.2022 | Schaffhausen Sharks | 20 – 14 | Dragons | NLC | N/A | 13 |
| 2022-06-19 14:00:0219.06.2022 | Calanda Broncos | 38 – 41 | Zurich Renegades | U19 Elite | N/A | 13 |
| 2022-06-19 14:30:0019.06.2022 | Bienna Jets | 37 – 0 | Fribourg Cardinals | NLB | N/A | 13 |
| 2022-06-19 15:00:0019.06.2022 | Rhein Fire | 42 – 12 | Rams | ELF | N/A | 13 |
| 2022-06-19 15:00:0019.06.2022 | Vikings | 42 – 13 | Stuttgart Surge | ELF | N/A | 13 |
| 2022-06-19 15:00:0019.06.2022 | Frankfurt Galaxy | 47 – 13 | Wroclaw Panthers | ELF | N/A | 13 |
| 2022-06-19 15:00:0019.06.2022 | Raiders | 28 – 16 | Berlin Thunder | ELF | N/A | 13 |
| 2022-06-25 18:00:0025.06.2022 | Cologne Centurions | 12 – 48 | Frankfurt Galaxy | ELF | N/A | 14 |
| 2022-06-25 18:00:0025.06.2022 | Rams | 0 – 49 | Vikings | ELF | N/A | 14 |
| 2022-06-25 18:00:0025.06.2022 | Orks | 48 – 0 | Niederbipp Ducks | NLC | N/A | 14 |
| 2022-06-26 11:00:4926.06.2022 | Thun Tigers | 46 – 47 | Zurich Renegades | U19 Elite | N/A | 14 |
| 2022-06-26 14:00:0026.06.2022 | Bern Grizzlies | 35 – 0 | Zurich Renegades | NLA | N/A | 14 |
| 2022-06-26 14:00:0026.06.2022 | Bienna Jets | 27 – 6 | Geneva Whoppers | NLB | N/A | 14 |
| 2022-06-26 14:00:0026.06.2022 | Luzern Lions | 9 – 2 | St. Gallen Bears | NLB | N/A | 14 |
| 2022-06-26 14:00:0026.06.2022 | Dragons | 25 – 19 | LUCAF Owls | NLC | N/A | 14 |
| 2022-06-26 14:00:0026.06.2022 | Langenthal Invaders | 48 – 6 | Lugano Rebels | NLC | N/A | 14 |
| 2022-06-26 14:30:0026.06.2022 | Zurich State Spartans | 20 – 0 | Morges Bandits | NLC | N/A | 14 |
| 2022-06-26 15:00:0026.06.2022 | Wroclaw Panthers | 23 – 26 | Hamburg Sea Devils | ELF | N/A | 14 |
| 2022-06-26 15:00:0026.06.2022 | Berlin Thunder | 15 – 19 | Leipzig Kings | ELF | N/A | 14 |
| 2022-06-26 15:00:0026.06.2022 | Raiders | 33 – 0 | Stuttgart Surge | ELF | N/A | 14 |
| 2022-06-26 15:00:0026.06.2022 | Rhein Fire | 13 – 17 | Barcelona Dragons | ELF | N/A | 14 |
| 2022-06-26 18:00:0026.06.2022 | Basel Gladiators | 34 – 6 | Thun Tigers | NLA | N/A | 14 |
| 2022-07-02 15:00:0002.07.2022 | Cologne Centurions | 7 – 34 | Berlin Thunder | ELF | N/A | 15 |
| 2022-07-02 18:00:0002.07.2022 | Argovia Pirates | 33 – 0 | Geneva Whoppers | NLB | N/A | 15 |
| 2022-07-02 18:00:0002.07.2022 | Barcelona Dragons | 41 – 7 | Rams | ELF | N/A | 15 |
| 2022-07-03 14:00:0003.07.2022 | Schaffhausen Sharks | 42 – 7 | Morges Bandits | NLC | N/A | 15 |
| 2022-07-03 14:00:0003.07.2022 | Zofingen Cheetahs | 0 – 42 | Neuchatel Knights | NLC | N/A | 15 |
| 2022-07-03 15:00:0003.07.2022 | Hamburg Sea Devils | 42 – 15 | Rhein Fire | ELF | N/A | 15 |
| 2022-07-03 15:00:0003.07.2022 | Vikings | 30 – 6 | Wroclaw Panthers | ELF | N/A | 15 |
| 2022-07-03 15:00:0003.07.2022 | Leipzig Kings | 28 – 22 | Stuttgart Surge | ELF | N/A | 15 |
| 2022-07-03 15:00:0003.07.2022 | Raiders | 23 – 17 | Frankfurt Galaxy | ELF | N/A | 15 |
| 2022-07-09 15:00:0009.07.2022 | Rams | 0 – 70 | Hamburg Sea Devils | ELF | N/A | 16 |
| 2022-07-09 18:00:0009.07.2022 | Barcelona Dragons | 20 – 27 | Vikings | ELF | N/A | 16 |
| 2022-07-09 18:00:0609.07.2022 | Bern Grizzlies | 45 – 0 | Thun Tigers | NLA | N/A | 16 |
| 2022-07-09 18:00:1109.07.2022 | Calanda Broncos | 38 – 14 | Basel Gladiators | NLA | N/A | 16 |
| 2022-07-09 18:00:1809.07.2022 | Langenthal Invaders | 28 – 0 | Dragons | NLC | N/A | 16 |
| 2022-07-10 14:00:4310.07.2022 | St. Gallen Bears | 10 – 6 | Luzern Lions | NLB | N/A | 16 |
| 2022-07-10 14:00:4610.07.2022 | Schaffhausen Sharks | 6 – 7 | Lugano Rebels | NLC | N/A | 16 |
| 2022-07-10 15:00:0010.07.2022 | Raiders | 37 – 6 | Leipzig Kings | ELF | N/A | 16 |
| 2022-07-10 15:00:0010.07.2022 | Berlin Thunder | 31 – 25 | Wroclaw Panthers | ELF | N/A | 16 |
| 2022-07-10 15:00:0010.07.2022 | Stuttgart Surge | 20 – 26 | Frankfurt Galaxy | ELF | N/A | 16 |
| 2022-07-10 15:00:0010.07.2022 | Rhein Fire | 17 – 3 | Cologne Centurions | ELF | N/A | 16 |
| 2022-07-16 14:30:0016.07.2022 | St. Gallen Bears | 6 – 20 | Zurich Renegades | NLA, NLB | N/A | 17 |
| 2022-07-16 18:00:2916.07.2022 | Bern Grizzlies | 26 – 22 | Calanda Broncos | NLA | N/A | 17 |
| 2022-07-17 14:00:3517.07.2022 | Langenthal Invaders | 28 – 7 | Lugano Rebels | NLC | N/A | 17 |
| 2022-07-17 15:00:0017.07.2022 | Leipzig Kings | 22 – 33 | Berlin Thunder | ELF | N/A | 17 |
| 2022-07-17 15:00:0017.07.2022 | Frankfurt Galaxy | 46 – 14 | Cologne Centurions | ELF | N/A | 17 |
| 2022-07-17 15:00:0017.07.2022 | Wroclaw Panthers | 34 – 0 | Stuttgart Surge | ELF | N/A | 17 |
| 2022-07-23 15:00:0023.07.2022 | Rams | 22 – 19 | Barcelona Dragons | ELF | N/A | 18 |
| 2022-07-24 15:00:0024.07.2022 | Rhein Fire | 16 – 40 | Hamburg Sea Devils | ELF | N/A | 18 |
| 2022-07-24 15:00:0024.07.2022 | Vikings | 29 – 13 | Raiders | ELF | N/A | 18 |
| 2022-07-30 15:00:0030.07.2022 | Stuttgart Surge | 0 – 41 | Vikings | ELF | N/A | 19 |
| 2022-07-30 18:00:0030.07.2022 | Barcelona Dragons | 32 – 23 | Rhein Fire | ELF | N/A | 19 |
| 2022-07-31 15:00:0031.07.2022 | Wroclaw Panthers | 29 – 30 | Frankfurt Galaxy | ELF | N/A | 19 |
| 2022-07-31 15:00:0031.07.2022 | Hamburg Sea Devils | 29 – 26 | Rams | ELF | N/A | 19 |
| 2022-07-31 15:00:0031.07.2022 | Leipzig Kings | 14 – 56 | Raiders | ELF | N/A | 19 |
| 2022-07-31 15:00:0031.07.2022 | Berlin Thunder | 39 – 29 | Cologne Centurions | ELF | N/A | 19 |
| 2022-08-13 12:00:0013.08.2022 | Cologne Centurions | 15 – 37 | Barcelona Dragons | ELF | N/A | 21 |
| 2022-08-13 12:00:0013.08.2022 | Rams | 32 – 50 | Rhein Fire | ELF | N/A | 21 |
| 2022-08-14 12:00:0014.08.2022 | Wroclaw Panthers | 12 – 29 | Berlin Thunder | ELF | N/A | 21 |
| 2022-08-14 12:00:0014.08.2022 | Hamburg Sea Devils | 59 – 0 | Leipzig Kings | ELF | N/A | 21 |
| 2022-08-14 12:00:0014.08.2022 | Frankfurt Galaxy | 42 – 8 | Vikings | ELF | N/A | 21 |
| 2022-08-14 12:00:0014.08.2022 | Raiders | 44 – 3 | Stuttgart Surge | ELF | N/A | 21 |
| 2022-08-20 12:00:0020.08.2022 | Barcelona Dragons | 62 – 8 | Stuttgart Surge | ELF | N/A | 22 |
| 2022-08-20 15:00:0020.08.2022 | Calanda Broncos | 42 – 6 | Winterthur Warriors | U16 | N/A | 1 |
| 2022-08-21 12:00:0021.08.2022 | Berlin Thunder | 17 – 39 | Hamburg Sea Devils | ELF | N/A | 22 |
| 2022-08-21 12:00:0021.08.2022 | Leipzig Kings | 37 – 41 | Wroclaw Panthers | ELF | N/A | 22 |
| 2022-08-21 12:00:0021.08.2022 | Rhein Fire | 23 – 21 | Frankfurt Galaxy | ELF | N/A | 22 |
| 2022-08-21 12:00:0021.08.2022 | Vikings | 37 – 22 | Rams | ELF | N/A | 22 |
| 2022-08-21 12:00:0021.08.2022 | Raiders | 45 – 20 | Cologne Centurions | ELF | N/A | 22 |
| 2022-08-21 14:00:0021.08.2022 | Thun Tigers | 56 – 8 | Zurich Renegades | U16 | N/A | 1 |
| 2022-08-21 14:30:0021.08.2022 | Bern Grizzlies | 13 – 12 | Basel Gladiators | U16 | N/A | 1 |
| 2022-08-27 12:00:0027.08.2022 | Cologne Centurions | 37 – 59 | Rhein Fire | ELF | N/A | 23 |
| 2022-08-27 12:00:0027.08.2022 | Rams | 14 – 38 | Berlin Thunder | ELF | N/A | 23 |
| 2022-08-27 15:00:0027.08.2022 | Calanda Broncos | 16 – 6 | Thun Tigers | U16 | N/A | 2 |
| 2022-08-28 12:00:0028.08.2022 | Vikings | 24 – 18 | Barcelona Dragons | ELF | N/A | 23 |
| 2022-08-28 12:00:0028.08.2022 | Stuttgart Surge | 0 – 38 | Leipzig Kings | ELF | N/A | 23 |
| 2022-08-28 12:00:0028.08.2022 | Frankfurt Galaxy | 36 – 33 | Raiders | ELF | N/A | 23 |
| 2022-08-28 12:00:0028.08.2022 | Hamburg Sea Devils | 17 – 0 | Wroclaw Panthers | ELF | N/A | 23 |
| 2022-08-28 14:00:0028.08.2022 | Winterthur Warriors | 16 – 0 | Bern Grizzlies | U16 | N/A | 2 |
| 2022-08-28 14:00:0028.08.2022 | Zurich Renegades | 44 – 14 | Basel Gladiators | U16 | N/A | 2 |
| 2022-09-03 12:00:0003.09.2022 | Rams | 30 – 43 | Cologne Centurions | ELF | N/A | 24 |
| 2022-09-03 12:00:0003.09.2022 | Barcelona Dragons | 21 – 24 | Hamburg Sea Devils | ELF | N/A | 24 |
| 2022-09-04 12:00:0004.09.2022 | Berlin Thunder | 10 – 37 | Raiders | ELF | N/A | 24 |
| 2022-09-04 12:00:0004.09.2022 | Rhein Fire | 31 – 34 | Leipzig Kings | ELF | N/A | 24 |
| 2022-09-04 12:00:0004.09.2022 | Wroclaw Panthers | 42 – 6 | Vikings | ELF | N/A | 24 |
| 2022-09-04 12:00:0004.09.2022 | Frankfurt Galaxy | 37 – 13 | Stuttgart Surge | ELF | N/A | 24 |
| 2022-09-04 14:00:0004.09.2022 | Basel Gladiators | 0 – 34 | Winterthur Warriors | U16 | N/A | 3 |
| 2022-09-04 14:00:0004.09.2022 | Thun Tigers | 42 – 0 | Bern Grizzlies | U16 | N/A | 3 |
| 2022-09-04 14:00:0004.09.2022 | Zurich Renegades | 6 – 40 | Calanda Broncos | U16 | N/A | 3 |
| 2022-09-09 02:20:0009.09.2022 | Los Angeles Rams | 10 – 31 | Buffalo Bills | NFL | N/A | 1 |
| 2022-09-10 15:00:0010.09.2022 | Bern Grizzlies | 0 – 32 | Calanda Broncos | U16 | N/A | 4 |
| 2022-09-11 14:00:0011.09.2022 | Basel Gladiators | 8 – 76 | Thun Tigers | U16 | N/A | 4 |
| 2022-09-11 14:00:0011.09.2022 | Winterthur Warriors | 22 – 38 | Zurich Renegades | U16 | N/A | 4 |
| 2022-09-11 19:00:0011.09.2022 | Atlanta Falcons | 26 – 27 | New Orleans Saints | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Carolina Panthers | 24 – 26 | Cleveland Browns | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Chicago Bears | 19 – 10 | San Francisco 49ers | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Cincinnati Bengals | 20 – 23 | Pittsburgh Steelers | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Detroit Lions | 35 – 38 | Philadelphia Eagles | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Houston Texans | 20 – 20 | Indianapolis Colts | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Miami Dolphins | 20 – 7 | New England Patriots | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | New York Jets | 9 – 24 | Baltimore Ravens | NFL | N/A | 1 |
| 2022-09-11 19:00:0011.09.2022 | Washington Commanders | 28 – 22 | Jacksonville Jaguars | NFL | N/A | 1 |
| 2022-09-11 22:25:0011.09.2022 | Arizona Cardinals | 22:25:0022:25 | Kansas City Chiefs | NFL | N/A | 1 |
| 2022-09-11 22:25:0011.09.2022 | Los Angeles Chargers | 24 – 19 | Las Vegas Raiders | NFL | N/A | 1 |
| 2022-09-11 22:25:0011.09.2022 | Minnesota Vikings | 23 – 7 | Green Bay Packers | NFL | N/A | 1 |
| 2022-09-11 22:25:0011.09.2022 | Tennessee Titans | 20 – 21 | New York Giants | NFL | N/A | 1 |
| 2022-09-12 02:20:0012.09.2022 | Dallas Cowboys | 3 – 19 | Tampa Bay Buccaneers | NFL | N/A | 1 |
| 2022-09-13 02:15:0013.09.2022 | Seattle Seahawks | 17 – 16 | Denver Broncos | NFL | N/A | 1 |
| 2022-09-16 02:15:0016.09.2022 | Kansas City Chiefs | 27 – 24 | Los Angeles Chargers | NFL | N/A | 2 |
| 2022-09-17 00:00:0017.09.2022 | Bye Week | 00:00:000:00 | Bye Week | U16 | N/A | 5 |
| 2022-09-18 19:00:0018.09.2022 | Baltimore Ravens | 38 – 42 | Miami Dolphins | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | Cleveland Browns | 30 – 31 | New York Jets | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | Detroit Lions | 36 – 27 | Washington Commanders | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | Jacksonville Jaguars | 24 – 0 | Indianapolis Colts | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | New Orleans Saints | 10 – 20 | Tampa Bay Buccaneers | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | New York Giants | 19 – 16 | Carolina Panthers | NFL | N/A | 2 |
| 2022-09-18 19:00:0018.09.2022 | Pittsburgh Steelers | 14 – 17 | New England Patriots | NFL | N/A | 2 |
| 2022-09-18 22:05:0018.09.2022 | Los Angeles Rams | 31 – 27 | Atlanta Falcons | NFL | N/A | 2 |
| 2022-09-18 22:05:0018.09.2022 | San Francisco 49ers | 27 – 7 | Seattle Seahawks | NFL | N/A | 2 |
| 2022-09-18 22:25:0018.09.2022 | Dallas Cowboys | 20 – 17 | Cincinnati Bengals | NFL | N/A | 2 |
| 2022-09-18 22:25:0018.09.2022 | Denver Broncos | 16 – 9 | Houston Texans | NFL | N/A | 2 |
| 2022-09-18 22:25:0018.09.2022 | Las Vegas Raiders | 23 – 29 | Arizona Cardinals | NFL | N/A | 2 |
| 2022-09-19 02:20:0019.09.2022 | Green Bay Packers | 27 – 10 | Chicago Bears | NFL | N/A | 2 |
| 2022-09-20 01:15:0020.09.2022 | Buffalo Bills | 41 – 7 | Tennessee Titans | NFL | N/A | 2 |
| 2022-09-20 02:30:0020.09.2022 | Philadelphia Eagles | 24 – 7 | Minnesota Vikings | NFL | N/A | 2 |
| 2022-09-23 02:15:0023.09.2022 | Cleveland Browns | 29 – 17 | Pittsburgh Steelers | NFL | N/A | 3 |
| 2022-09-24 15:00:0024.09.2022 | Calanda Broncos | 44 – 14 | Basel Gladiators | U16 | N/A | 6 |
| 2022-09-25 12:00:3625.09.2022 | Hamburg Sea Devils | 15 – 27 | Vikings | ELF | N/A | – |
| 2022-09-25 14:00:0025.09.2022 | Thun Tigers | 6 – 28 | Winterthur Warriors | U16 | N/A | 6 |
| 2022-09-25 14:00:0025.09.2022 | Zurich Renegades | 26 – 0 | Bern Grizzlies | U16 | N/A | 6 |
| 2022-09-25 19:00:0025.09.2022 | Carolina Panthers | 22 – 14 | New Orleans Saints | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Chicago Bears | 23 – 20 | Houston Texans | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Indianapolis Colts | 20 – 17 | Kansas City Chiefs | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Miami Dolphins | 21 – 19 | Buffalo Bills | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Minnesota Vikings | 28 – 24 | Detroit Lions | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | New England Patriots | 26 – 37 | Baltimore Ravens | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | New York Jets | 12 – 27 | Cincinnati Bengals | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Tennessee Titans | 24 – 22 | Las Vegas Raiders | NFL | N/A | 3 |
| 2022-09-25 19:00:0025.09.2022 | Washington Commanders | 8 – 24 | Philadelphia Eagles | NFL | N/A | 3 |
| 2022-09-25 22:05:0025.09.2022 | Los Angeles Chargers | 10 – 38 | Jacksonville Jaguars | NFL | N/A | 3 |
| 2022-09-25 22:25:0025.09.2022 | Arizona Cardinals | 12 – 20 | Los Angeles Rams | NFL | N/A | 3 |
| 2022-09-25 22:25:0025.09.2022 | Seattle Seahawks | 23 – 27 | Atlanta Falcons | NFL | N/A | 3 |
| 2022-09-25 22:25:0025.09.2022 | Tampa Bay Buccaneers | 12 – 14 | Green Bay Packers | NFL | N/A | 3 |
| 2022-09-26 02:20:0026.09.2022 | Denver Broncos | 11 – 10 | San Francisco 49ers | NFL | N/A | 3 |
| 2022-09-27 02:15:0027.09.2022 | New York Giants | 16 – 23 | Dallas Cowboys | NFL | N/A | 3 |
| 2022-09-30 02:15:0030.09.2022 | Cincinnati Bengals | 27 – 15 | Miami Dolphins | NFL | N/A | 4 |
| 2022-10-01 00:00:0001.10.2022 | Grossbritannien | 1 – 0 | Russland | European Championships | N/A | – |
| 2022-10-01 00:00:0001.10.2022 | Italien | 1 – 0 | Russland | European Championships | N/A | – |
| 2022-10-01 15:00:0001.10.2022 | Bern Grizzlies | 0 – 34 | Thun Tigers | U16 | N/A | 7 |
| 2022-10-02 14:00:0002.10.2022 | Basel Gladiators | 0 – 56 | Zurich Renegades | U16 | N/A | 7 |
| 2022-10-02 15:30:0002.10.2022 | New Orleans Saints | 25 – 28 | Minnesota Vikings | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Atlanta Falcons | 23 – 20 | Cleveland Browns | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Baltimore Ravens | 20 – 23 | Buffalo Bills | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Dallas Cowboys | 25 – 10 | Washington Commanders | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Detroit Lions | 45 – 48 | Seattle Seahawks | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Houston Texans | 24 – 34 | Los Angeles Chargers | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Indianapolis Colts | 17 – 24 | Tennessee Titans | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | New York Giants | 20 – 12 | Chicago Bears | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Philadelphia Eagles | 29 – 21 | Jacksonville Jaguars | NFL | N/A | 4 |
| 2022-10-02 19:00:0002.10.2022 | Pittsburgh Steelers | 20 – 24 | New York Jets | NFL | N/A | 4 |
| 2022-10-02 22:05:0002.10.2022 | Carolina Panthers | 16 – 26 | Arizona Cardinals | NFL | N/A | 4 |
| 2022-10-02 22:25:0002.10.2022 | Green Bay Packers | 27 – 24 | New England Patriots | NFL | N/A | 4 |
| 2022-10-02 22:25:0002.10.2022 | Las Vegas Raiders | 32 – 23 | Denver Broncos | NFL | N/A | 4 |
| 2022-10-03 02:20:0003.10.2022 | Tampa Bay Buccaneers | 31 – 41 | Kansas City Chiefs | NFL | N/A | 4 |
| 2022-10-04 02:15:0004.10.2022 | San Francisco 49ers | 24 – 9 | Los Angeles Rams | NFL | N/A | 4 |
| 2022-10-07 02:15:0007.10.2022 | Denver Broncos | 02:15:002:15 | Indianapolis Colts | NFL | N/A | 5 |
| 2022-10-08 00:00:0008.10.2022 | Finnland | 60 – 13 | Daenemark | European Championships | N/A | – |
| 2022-10-08 00:00:0008.10.2022 | Schweden | 21 – 14 | Serbien | European Championships | N/A | – |
| 2022-10-09 00:00:0009.10.2022 | Frankreich | 7 – 35 | Oesterreich | European Championships | N/A | – |
| 2022-10-09 14:00:0009.10.2022 | Winterthur Warriors | 22 – 44 | Calanda Broncos | U16 | N/A | 7 |
| 2022-10-09 15:30:0009.10.2022 | Green Bay Packers | 22 – 27 | New York Giants | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Buffalo Bills | 38 – 3 | Pittsburgh Steelers | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Cleveland Browns | 28 – 30 | Los Angeles Chargers | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Jacksonville Jaguars | 6 – 13 | Houston Texans | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Minnesota Vikings | 29 – 22 | Chicago Bears | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | New England Patriots | 29 – 0 | Detroit Lions | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | New Orleans Saints | 39 – 32 | Seattle Seahawks | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | New York Jets | 40 – 17 | Miami Dolphins | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Tampa Bay Buccaneers | 21 – 15 | Atlanta Falcons | NFL | N/A | 5 |
| 2022-10-09 19:00:0009.10.2022 | Washington Commanders | 17 – 21 | Tennessee Titans | NFL | N/A | 5 |
| 2022-10-09 22:05:0009.10.2022 | Carolina Panthers | 15 – 37 | San Francisco 49ers | NFL | N/A | 5 |
| 2022-10-09 22:25:0009.10.2022 | Arizona Cardinals | 17 – 20 | Philadelphia Eagles | NFL | N/A | 5 |
| 2022-10-09 22:25:0009.10.2022 | Los Angeles Rams | 10 – 22 | Dallas Cowboys | NFL | N/A | 5 |
| 2022-10-10 02:20:0010.10.2022 | Baltimore Ravens | 19 – 17 | Cincinnati Bengals | NFL | N/A | 5 |
| 2022-10-11 02:15:0011.10.2022 | Kansas City Chiefs | 02:15:002:15 | Las Vegas Raiders | NFL | N/A | 5 |
| 2022-10-14 02:15:0014.10.2022 | Chicago Bears | 02:15:002:15 | Washington Commanders | NFL | N/A | 6 |
| 2022-10-15 12:00:2815.10.2022 | Calanda Broncos | 12:00:2812:00 | Winterthur Warriors | U16 | N/A | – |
| 2022-10-15 12:00:5815.10.2022 | Thun Tigers | 12:00:5812:00 | Zurich Renegades | U16 | N/A | – |
| 2022-10-16 00:00:0016.10.2022 | Tschechien | 10 – 42 | Finnland | European Championships | N/A | – |
| 2022-10-16 14:00:0016.10.2022 | Schweiz | 6 – 31 | Schweden | European Championships | N/A | – |
| 2022-10-16 19:00:0016.10.2022 | Atlanta Falcons | 28 – 14 | San Francisco 49ers | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | Cleveland Browns | 15 – 38 | New England Patriots | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | Green Bay Packers | 10 – 27 | New York Jets | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | Indianapolis Colts | 34 – 27 | Jacksonville Jaguars | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | Miami Dolphins | 16 – 24 | Minnesota Vikings | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | New Orleans Saints | 26 – 30 | Cincinnati Bengals | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | New York Giants | 24 – 20 | Baltimore Ravens | NFL | N/A | 6 |
| 2022-10-16 19:00:0016.10.2022 | Pittsburgh Steelers | 20 – 18 | Tampa Bay Buccaneers | NFL | N/A | 6 |
| 2022-10-16 22:05:0016.10.2022 | Los Angeles Rams | 24 – 10 | Carolina Panthers | NFL | N/A | 6 |
| 2022-10-16 22:05:0016.10.2022 | Seattle Seahawks | 19 – 9 | Arizona Cardinals | NFL | N/A | 6 |
| 2022-10-16 22:25:0016.10.2022 | Kansas City Chiefs | 20 – 24 | Buffalo Bills | NFL | N/A | 6 |
| 2022-10-17 02:20:0017.10.2022 | Philadelphia Eagles | 26 – 17 | Dallas Cowboys | NFL | N/A | 6 |
| 2022-10-18 02:15:0018.10.2022 | Los Angeles Chargers | 19 – 16 | Denver Broncos | NFL | N/A | 6 |
| 2022-10-21 02:15:0021.10.2022 | Arizona Cardinals | 42 – 34 | New Orleans Saints | NFL | N/A | 7 |
| 2022-10-23 00:00:0023.10.2022 | Oesterreich | 41 – 0 | Ungarn | European Championships | N/A | – |
| 2022-10-23 14:00:0023.10.2022 | Calanda Broncos | 46 – 22 | Thun Tigers | U16 | N/A | 10 |
| 2022-10-23 14:00:0023.10.2022 | Serbien | 24 – 13 | Schweiz | European Championships | N/A | – |
| 2022-10-23 19:00:0023.10.2022 | Baltimore Ravens | 23 – 20 | Cleveland Browns | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Carolina Panthers | 21 – 3 | Tampa Bay Buccaneers | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Cincinnati Bengals | 35 – 17 | Atlanta Falcons | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Dallas Cowboys | 24 – 6 | Detroit Lions | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Jacksonville Jaguars | 17 – 23 | New York Giants | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Tennessee Titans | 19 – 10 | Indianapolis Colts | NFL | N/A | 7 |
| 2022-10-23 19:00:0023.10.2022 | Washington Commanders | 23 – 21 | Green Bay Packers | NFL | N/A | 7 |
| 2022-10-23 22:05:0023.10.2022 | Denver Broncos | 9 – 16 | New York Jets | NFL | N/A | 7 |
| 2022-10-23 22:05:0023.10.2022 | Las Vegas Raiders | 38 – 20 | Houston Texans | NFL | N/A | 7 |
| 2022-10-23 22:25:0023.10.2022 | Los Angeles Chargers | 23 – 37 | Seattle Seahawks | NFL | N/A | 7 |
| 2022-10-23 22:25:0023.10.2022 | San Francisco 49ers | 23 – 44 | Kansas City Chiefs | NFL | N/A | 7 |
| 2022-10-24 02:20:0024.10.2022 | Miami Dolphins | 16 – 10 | Pittsburgh Steelers | NFL | N/A | 7 |
| 2022-10-25 02:15:0025.10.2022 | New England Patriots | 14 – 33 | Chicago Bears | NFL | N/A | 7 |
| 2022-10-28 02:15:0028.10.2022 | Tampa Bay Buccaneers | 22 – 27 | Baltimore Ravens | NFL | N/A | 8 |
| 2022-10-29 00:00:0029.10.2022 | Daenemark | 45 – 40 | Tschechien | European Championships | N/A | – |
| 2022-10-30 00:00:0030.10.2022 | Italien | 28 – 23 | Grossbritannien | European Championships | N/A | – |
| 2022-10-30 14:30:0030.10.2022 | Jacksonville Jaguars | 17 – 21 | Denver Broncos | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | Atlanta Falcons | 37 – 34 | Carolina Panthers | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | Dallas Cowboys | 49 – 29 | Chicago Bears | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | Detroit Lions | 27 – 31 | Miami Dolphins | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | Minnesota Vikings | 34 – 26 | Arizona Cardinals | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | New Orleans Saints | 24 – 0 | Las Vegas Raiders | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | New York Jets | 17 – 22 | New England Patriots | NFL | N/A | 8 |
| 2022-10-30 18:00:0030.10.2022 | Philadelphia Eagles | 35 – 13 | Pittsburgh Steelers | NFL | N/A | 8 |
| 2022-10-30 21:05:0030.10.2022 | Houston Texans | 10 – 17 | Tennessee Titans | NFL | N/A | 8 |
| 2022-10-30 21:25:0030.10.2022 | Indianapolis Colts | 16 – 17 | Washington Commanders | NFL | N/A | 8 |
| 2022-10-30 21:25:0030.10.2022 | Los Angeles Rams | 14 – 31 | San Francisco 49ers | NFL | N/A | 8 |
| 2022-10-30 21:25:0030.10.2022 | Seattle Seahawks | 27 – 13 | New York Giants | NFL | N/A | 8 |
| 2022-10-31 01:20:0031.10.2022 | Buffalo Bills | 27 – 17 | Green Bay Packers | NFL | N/A | 8 |
| 2022-11-01 01:15:0001.11.2022 | Cleveland Browns | 32 – 13 | Cincinnati Bengals | NFL | N/A | 8 |
| 2022-11-04 01:15:0004.11.2022 | Houston Texans | 17 – 29 | Philadelphia Eagles | NFL | N/A | 9 |
| 2022-11-05 00:00:0005.11.2022 | Ungarn | 2 – 9 | Frankreich | European Championships | N/A | – |
| 2022-11-06 19:00:0006.11.2022 | Atlanta Falcons | 17 – 20 | Los Angeles Chargers | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | Chicago Bears | 32 – 35 | Miami Dolphins | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | Cincinnati Bengals | 42 – 21 | Carolina Panthers | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | Detroit Lions | 15 – 9 | Green Bay Packers | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | Jacksonville Jaguars | 27 – 20 | Las Vegas Raiders | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | New England Patriots | 26 – 3 | Indianapolis Colts | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | New York Jets | 20 – 17 | Buffalo Bills | NFL | N/A | 9 |
| 2022-11-06 19:00:0006.11.2022 | Washington Commanders | 17 – 20 | Minnesota Vikings | NFL | N/A | 9 |
| 2022-11-06 22:05:0006.11.2022 | Arizona Cardinals | 21 – 31 | Seattle Seahawks | NFL | N/A | 9 |
| 2022-11-06 22:25:0006.11.2022 | Tampa Bay Buccaneers | 16 – 13 | Los Angeles Rams | NFL | N/A | 9 |
| 2022-11-07 02:20:0007.11.2022 | Kansas City Chiefs | 20 – 17 | Tennessee Titans | NFL | N/A | 9 |
| 2022-11-08 02:15:0008.11.2022 | New Orleans Saints | 02:15:002:15 | Baltimore Ravens | NFL | N/A | 9 |
| 2022-11-11 02:15:0011.11.2022 | Carolina Panthers | 25 – 15 | Atlanta Falcons | NFL | N/A | 10 |
| 2022-11-13 15:30:0013.11.2022 | Tampa Bay Buccaneers | 21 – 16 | Seattle Seahawks | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Buffalo Bills | 30 – 33 | Minnesota Vikings | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Chicago Bears | 30 – 31 | Detroit Lions | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Kansas City Chiefs | 27 – 17 | Jacksonville Jaguars | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Miami Dolphins | 39 – 17 | Cleveland Browns | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | New York Giants | 24 – 16 | Houston Texans | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Pittsburgh Steelers | 20 – 10 | New Orleans Saints | NFL | N/A | 10 |
| 2022-11-13 19:00:0013.11.2022 | Tennessee Titans | 17 – 10 | Denver Broncos | NFL | N/A | 10 |
| 2022-11-13 22:05:0013.11.2022 | Las Vegas Raiders | 20 – 25 | Indianapolis Colts | NFL | N/A | 10 |
| 2022-11-13 22:25:0013.11.2022 | Green Bay Packers | 31 – 28 | Dallas Cowboys | NFL | N/A | 10 |
| 2022-11-13 22:25:0013.11.2022 | Los Angeles Rams | 17 – 27 | Arizona Cardinals | NFL | N/A | 10 |
| 2022-11-14 02:20:0014.11.2022 | San Francisco 49ers | 22 – 16 | Los Angeles Chargers | NFL | N/A | 10 |
| 2022-11-15 02:15:0015.11.2022 | Philadelphia Eagles | 21 – 32 | Washington Commanders | NFL | N/A | 10 |
| 2022-11-18 02:15:0018.11.2022 | Green Bay Packers | 17 – 27 | Tennessee Titans | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | Atlanta Falcons | 27 – 24 | Chicago Bears | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | Baltimore Ravens | 13 – 3 | Carolina Panthers | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | Buffalo Bills | 31 – 23 | Cleveland Browns | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | Houston Texans | 10 – 23 | Washington Commanders | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | Indianapolis Colts | 16 – 17 | Philadelphia Eagles | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | New England Patriots | 10 – 3 | New York Jets | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | New Orleans Saints | 27 – 20 | Los Angeles Rams | NFL | N/A | 11 |
| 2022-11-20 19:00:0020.11.2022 | New York Giants | 18 – 31 | Detroit Lions | NFL | N/A | 11 |
| 2022-11-20 22:05:0020.11.2022 | Denver Broncos | 16 – 22 | Las Vegas Raiders | NFL | N/A | 11 |
| 2022-11-20 22:25:0020.11.2022 | Los Angeles Chargers | 27 – 30 | Kansas City Chiefs | NFL | N/A | 11 |
| 2022-11-20 22:25:0020.11.2022 | Minnesota Vikings | 3 – 40 | Dallas Cowboys | NFL | N/A | 11 |
| 2022-11-21 02:20:0021.11.2022 | Pittsburgh Steelers | 30 – 37 | Cincinnati Bengals | NFL | N/A | 11 |
| 2022-11-22 01:15:0022.11.2022 | Arizona Cardinals | 10 – 38 | San Francisco 49ers | NFL | N/A | 11 |
| 2022-11-24 18:30:0024.11.2022 | Detroit Lions | 25 – 28 | Buffalo Bills | NFL | N/A | 12 |
| 2022-11-24 22:30:0024.11.2022 | Dallas Cowboys | 28 – 20 | New York Giants | NFL | N/A | 12 |
| 2022-11-25 02:20:0025.11.2022 | Minnesota Vikings | 33 – 26 | New England Patriots | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Carolina Panthers | 23 – 10 | Denver Broncos | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Cleveland Browns | 23 – 17 | Tampa Bay Buccaneers | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Jacksonville Jaguars | 28 – 27 | Baltimore Ravens | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Miami Dolphins | 30 – 15 | Houston Texans | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | New York Jets | 31 – 10 | Chicago Bears | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Tennessee Titans | 16 – 20 | Cincinnati Bengals | NFL | N/A | 12 |
| 2022-11-27 19:00:0027.11.2022 | Washington Commanders | 19 – 13 | Atlanta Falcons | NFL | N/A | 12 |
| 2022-11-27 22:05:0027.11.2022 | Arizona Cardinals | 24 – 25 | Los Angeles Chargers | NFL | N/A | 12 |
| 2022-11-27 22:05:0027.11.2022 | Seattle Seahawks | 34 – 40 | Las Vegas Raiders | NFL | N/A | 12 |
| 2022-11-27 22:25:0027.11.2022 | Kansas City Chiefs | 26 – 10 | Los Angeles Rams | NFL | N/A | 12 |
| 2022-11-27 22:25:0027.11.2022 | San Francisco 49ers | 13 – 0 | New Orleans Saints | NFL | N/A | 12 |
| 2022-11-28 02:20:0028.11.2022 | Philadelphia Eagles | 40 – 33 | Green Bay Packers | NFL | N/A | 12 |
| 2022-11-29 02:15:0029.11.2022 | Indianapolis Colts | 17 – 24 | Pittsburgh Steelers | NFL | N/A | 12 |
| 2022-12-02 02:15:0002.12.2022 | New England Patriots | 10 – 24 | Buffalo Bills | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Atlanta Falcons | 16 – 19 | Pittsburgh Steelers | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Baltimore Ravens | 10 – 9 | Denver Broncos | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Chicago Bears | 19 – 28 | Green Bay Packers | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Detroit Lions | 40 – 14 | Jacksonville Jaguars | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Houston Texans | 14 – 27 | Cleveland Browns | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Minnesota Vikings | 27 – 22 | New York Jets | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | New York Giants | 20 – 20 | Washington Commanders | NFL | N/A | 13 |
| 2022-12-04 19:00:0004.12.2022 | Philadelphia Eagles | 35 – 10 | Tennessee Titans | NFL | N/A | 13 |
| 2022-12-04 22:05:0004.12.2022 | Los Angeles Rams | 23 – 27 | Seattle Seahawks | NFL | N/A | 13 |
| 2022-12-04 22:05:0004.12.2022 | San Francisco 49ers | 33 – 17 | Miami Dolphins | NFL | N/A | 13 |
| 2022-12-04 22:25:0004.12.2022 | Cincinnati Bengals | 27 – 24 | Kansas City Chiefs | NFL | N/A | 13 |
| 2022-12-04 22:25:0004.12.2022 | Las Vegas Raiders | 27 – 20 | Los Angeles Chargers | NFL | N/A | 13 |
| 2022-12-05 02:20:0005.12.2022 | Dallas Cowboys | 54 – 19 | Indianapolis Colts | NFL | N/A | 13 |
| 2022-12-06 02:15:0006.12.2022 | Tampa Bay Buccaneers | 17 – 16 | New Orleans Saints | NFL | N/A | 13 |
| 2022-12-09 02:15:0009.12.2022 | Los Angeles Rams | 17 – 16 | Las Vegas Raiders | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Buffalo Bills | 20 – 12 | New York Jets | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Cincinnati Bengals | 23 – 10 | Cleveland Browns | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Dallas Cowboys | 27 – 23 | Houston Texans | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Detroit Lions | 34 – 23 | Minnesota Vikings | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | New York Giants | 22 – 48 | Philadelphia Eagles | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Pittsburgh Steelers | 14 – 16 | Baltimore Ravens | NFL | N/A | 14 |
| 2022-12-11 19:00:0011.12.2022 | Tennessee Titans | 22 – 36 | Jacksonville Jaguars | NFL | N/A | 14 |
| 2022-12-11 22:05:0011.12.2022 | Los Angeles Chargers | 23 – 17 | Miami Dolphins | NFL | N/A | 14 |
| 2022-12-11 22:25:0011.12.2022 | San Francisco 49ers | 35 – 7 | Tampa Bay Buccaneers | NFL | N/A | 14 |
| 2022-12-11 22:25:0011.12.2022 | Seattle Seahawks | 24 – 30 | Carolina Panthers | NFL | N/A | 14 |
| 2022-12-12 02:20:0012.12.2022 | Denver Broncos | 28 – 34 | Kansas City Chiefs | NFL | N/A | 14 |
| 2022-12-13 02:15:0013.12.2022 | Arizona Cardinals | 13 – 27 | New England Patriots | NFL | N/A | 14 |
| 2022-12-16 02:15:0016.12.2022 | Seattle Seahawks | 13 – 21 | San Francisco 49ers | NFL | N/A | 15 |
| 2022-12-18 00:00:0018.12.2022 | Buffalo Bills | 32 – 29 | Miami Dolphins | NFL | N/A | 15 |
| 2022-12-18 00:00:0018.12.2022 | Cleveland Browns | 13 – 3 | Baltimore Ravens | NFL | N/A | 15 |
| 2022-12-18 00:00:0018.12.2022 | Minnesota Vikings | 39 – 36 | Indianapolis Colts | NFL | N/A | 15 |
| 2022-12-18 00:00:0018.12.2022 | New Orleans Saints | 21 – 18 | Atlanta Falcons | NFL | N/A | 15 |
| 2022-12-18 00:00:0018.12.2022 | Washington Commanders | 12 – 20 | New York Giants | NFL | N/A | 15 |
| 2022-12-18 19:00:0018.12.2022 | Carolina Panthers | 16 – 24 | Pittsburgh Steelers | NFL | N/A | 15 |
| 2022-12-18 19:00:0018.12.2022 | Chicago Bears | 20 – 25 | Philadelphia Eagles | NFL | N/A | 15 |
| 2022-12-18 19:00:0018.12.2022 | Houston Texans | 24 – 30 | Kansas City Chiefs | NFL | N/A | 15 |
| 2022-12-18 19:00:0018.12.2022 | Jacksonville Jaguars | 40 – 34 | Dallas Cowboys | NFL | N/A | 15 |
| 2022-12-18 19:00:0018.12.2022 | New York Jets | 17 – 20 | Detroit Lions | NFL | N/A | 15 |
| 2022-12-18 22:05:0018.12.2022 | Denver Broncos | 24 – 15 | Arizona Cardinals | NFL | N/A | 15 |
| 2022-12-18 22:25:0018.12.2022 | Los Angeles Chargers | 17 – 14 | Tennessee Titans | NFL | N/A | 15 |
| 2022-12-18 22:25:0018.12.2022 | Tampa Bay Buccaneers | 23 – 34 | Cincinnati Bengals | NFL | N/A | 15 |
| 2022-12-19 02:20:0019.12.2022 | Las Vegas Raiders | 30 – 24 | New England Patriots | NFL | N/A | 15 |
| 2022-12-20 02:15:0020.12.2022 | Green Bay Packers | 24 – 12 | Los Angeles Rams | NFL | N/A | 15 |
| 2022-12-23 02:15:0023.12.2022 | New York Jets | 3 – 19 | Jacksonville Jaguars | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Baltimore Ravens | 17 – 9 | Atlanta Falcons | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Carolina Panthers | 37 – 23 | Detroit Lions | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Chicago Bears | 13 – 35 | Buffalo Bills | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Cleveland Browns | 10 – 17 | New Orleans Saints | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Kansas City Chiefs | 24 – 10 | Seattle Seahawks | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Minnesota Vikings | 27 – 24 | New York Giants | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | New England Patriots | 18 – 22 | Cincinnati Bengals | NFL | N/A | 16 |
| 2022-12-24 19:00:0024.12.2022 | Tennessee Titans | 14 – 19 | Houston Texans | NFL | N/A | 16 |
| 2022-12-24 22:05:0024.12.2022 | San Francisco 49ers | 37 – 20 | Washington Commanders | NFL | N/A | 16 |
| 2022-12-24 22:25:0024.12.2022 | Dallas Cowboys | 40 – 34 | Philadelphia Eagles | NFL | N/A | 16 |
| 2022-12-25 02:15:0025.12.2022 | Pittsburgh Steelers | 13 – 10 | Las Vegas Raiders | NFL | N/A | 16 |
| 2022-12-25 19:00:0025.12.2022 | Miami Dolphins | 20 – 26 | Green Bay Packers | NFL | N/A | 16 |
| 2022-12-25 22:30:0025.12.2022 | Los Angeles Rams | 51 – 14 | Denver Broncos | NFL | N/A | 16 |
| 2022-12-26 02:20:0026.12.2022 | Arizona Cardinals | 16 – 19 | Tampa Bay Buccaneers | NFL | N/A | 16 |
| 2022-12-27 02:15:0027.12.2022 | Indianapolis Colts | 3 – 20 | Los Angeles Chargers | NFL | N/A | 16 |
| 2022-12-30 02:15:0030.12.2022 | Tennessee Titans | 13 – 27 | Dallas Cowboys | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Atlanta Falcons | 20 – 19 | Arizona Cardinals | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Baltimore Ravens | 13 – 16 | Pittsburgh Steelers | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Detroit Lions | 41 – 10 | Chicago Bears | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Houston Texans | 3 – 31 | Jacksonville Jaguars | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Kansas City Chiefs | 27 – 24 | Denver Broncos | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | New England Patriots | 23 – 21 | Miami Dolphins | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | New York Giants | 38 – 10 | Indianapolis Colts | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Philadelphia Eagles | 10 – 20 | New Orleans Saints | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Tampa Bay Buccaneers | 30 – 24 | Carolina Panthers | NFL | N/A | 17 |
| 2023-01-01 19:00:0001.01.2023 | Washington Commanders | 10 – 24 | Cleveland Browns | NFL | N/A | 17 |
| 2023-01-01 22:05:0001.01.2023 | Las Vegas Raiders | 34 – 37 | San Francisco 49ers | NFL | N/A | 17 |
| 2023-01-01 22:05:0001.01.2023 | Seattle Seahawks | 23 – 6 | New York Jets | NFL | N/A | 17 |
| 2023-01-01 22:25:0001.01.2023 | Green Bay Packers | 41 – 17 | Minnesota Vikings | NFL | N/A | 17 |
| 2023-01-02 02:20:0002.01.2023 | Los Angeles Chargers | 31 – 10 | Los Angeles Rams | NFL | N/A | 17 |
| 2023-01-03 02:30:0003.01.2023 | Cincinnati Bengals | 27 – 16 | Buffalo Bills | NFL | N/A | 17 |
| 2023-01-08 00:00:0008.01.2023 | Atlanta Falcons | 30 – 17 | Tampa Bay Buccaneers | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Buffalo Bills | 35 – 23 | New England Patriots | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Chicago Bears | 13 – 29 | Minnesota Vikings | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Cincinnati Bengals | 27 – 16 | Baltimore Ravens | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Denver Broncos | 31 – 28 | Los Angeles Chargers | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Green Bay Packers | 16 – 20 | Detroit Lions | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Indianapolis Colts | 31 – 32 | Houston Texans | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Jacksonville Jaguars | 20 – 16 | Tennessee Titans | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Las Vegas Raiders | 13 – 31 | Kansas City Chiefs | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Miami Dolphins | 11 – 6 | New York Jets | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | New Orleans Saints | 7 – 10 | Carolina Panthers | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Philadelphia Eagles | 22 – 16 | New York Giants | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Pittsburgh Steelers | 28 – 14 | Cleveland Browns | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | San Francisco 49ers | 38 – 13 | Arizona Cardinals | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Seattle Seahawks | 19 – 16 | Los Angeles Rams | NFL | N/A | 18 |
| 2023-01-08 00:00:0008.01.2023 | Washington Commanders | 26 – 6 | Dallas Cowboys | NFL | N/A | 18 |
| 2023-01-14 22:30:0014.01.2023 | San Francisco 49er | 41 – 23 | Seattle Seahawks | NFL | N/A | 19 |
| 2023-01-15 02:15:0015.01.2023 | Jacksonville Jaguars | 31 – 30 | Los Angeles Chargers | NFL | N/A | 19 |
| 2023-01-15 19:00:0015.01.2023 | Buffalo Bills | 34 – 31 | Miami Dolphins | NFL | N/A | 19 |
| 2023-01-15 22:30:0015.01.2023 | Minnesota Vikings | 24 – 31 | New York Giants | NFL | N/A | 19 |
| 2023-01-16 02:15:0016.01.2023 | Cincinatti Bengals | 24 – 17 | Baltimore Ravens | NFL | N/A | 19 |
| 2023-01-17 02:15:0017.01.2023 | Tampa Bay Buccaneers | 14 – 31 | Dallas Cowboys | NFL | N/A | 19 |
| 2023-01-21 02:15:0021.01.2023 | Philadelphia Eagles | 38 – 7 | New York Giants | NFL | N/A | 20 |
| 2023-01-21 22:30:0021.01.2023 | Kansas City Chiefs | 27 – 20 | Jacksonville Jaguars | NFL | N/A | 20 |
| 2023-01-22 00:30:0022.01.2023 | San Francisco 49ers | 19 – 12 | Dallas Cowboys | NFL | N/A | 20 |
| 2023-01-22 21:00:0022.01.2023 | Buffalo Bills | 10 – 27 | Cincinatti Bengals | NFL | N/A | 20 |
| 2023-01-29 21:00:0029.01.2023 | Philadelphia Eagles | 31 – 7 | San Francisco 49ers | NFL | N/A | 21 |
| 2023-01-30 00:30:0030.01.2023 | Kansas City Chiefs | 23 – 20 | Cincinnati Bengals | NFL | N/A | 21 |
| 2023-02-13 00:30:3713.02.2023 | Philadelphia Eagles | 00:30:370:30 | Kansas City Chiefs | NFL | N/A | 22 |
