| 2022-03-26 14:30:0026.03.2022 | Winterthur Warriors | 14 – 6 | Argovia Pirates | U19 Elite | 1 |
| 2022-03-26 15:00:0026.03.2022 | LUCAF Owls | 0 – 32 | Lugano Rebels | NLC | 1 |
| 2022-03-26 18:00:0026.03.2022 | Winterthur Warriors | 6 – 34 | Bern Grizzlies | NLA | 1 |
| 2022-03-27 11:00:0027.03.2022 | Geneva Seahawks | 30 – 12 | Bern Grizzlies | U19 Elite | 1 |
| 2022-03-27 14:00:0027.03.2022 | Morges Bandits | 28 – 20 | Orks | NLC | 1 |
| 2022-03-27 14:00:0027.03.2022 | Neuchatel Knights | 3 – 14 | Zurich State Spartans | NLC | 1 |
| 2022-03-27 14:00:0027.03.2022 | Niederbipp Ducks | 6 – 53 | Dragons | NLC | 1 |
| 2022-03-27 14:00:0027.03.2022 | Schaffhausen Sharks | 3 – 0 | Langenthal Invaders | NLC | 1 |
| 2022-03-27 14:30:0027.03.2022 | Geneva Seahawks | 13 – 0 | Zurich Renegades | NLA | 1 |
| 2022-04-02 14:00:2002.04.2022 | Black Panthers | 12 – 6 | Las Rozas Black Demons | CEFL | – |
| 2022-04-03 11:00:0003.04.2022 | Calanda Broncos | 59 – 22 | Basel Gladiators | U19 Elite | 2 |
| 2022-04-03 14:00:0003.04.2022 | Zurich State Spartans | 10 – 8 | Langenthal Invaders | NLC | 2 |
| 2022-04-03 14:30:0003.04.2022 | Calanda Broncos | 49 – 21 | Thun Tigers | NLA | 2 |
| 2022-04-10 11:00:0010.04.2022 | Basel Gladiators | 35 – 44 | Argovia Pirates | U19 Elite | 3 |
| 2022-04-10 11:00:0010.04.2022 | Bern Grizzlies | 8 – 25 | Zurich Renegades | U19 Elite | 3 |
| 2022-04-10 11:00:0010.04.2022 | St. Gallen Bears | 7 – 44 | Geneva Seahawks | U19 Elite | 3 |
| 2022-04-10 11:00:0010.04.2022 | Thun Tigers | 48 – 8 | Winterthur Warriors | U19 Elite | 3 |
| 2022-04-10 11:00:0010.04.2022 | Luzern Lions | 18 – 22 | Bienna Jets | U19 Challenge League | 3 |
| 2022-04-10 14:00:0010.04.2022 | Luzern Lions | 33 – 13 | Bienna Jets | NLB | 3 |
| 2022-04-10 14:00:0010.04.2022 | Dragons | 50 – 0 | Zofingen Cheetahs | NLC | 3 |
| 2022-04-10 14:00:0010.04.2022 | Niederbipp Ducks | 0 – 24 | Neuchatel Knights | NLC | 3 |
| 2022-04-10 14:30:0010.04.2022 | Bern Grizzlies | 27 – 0 | Geneva Seahawks | NLA | 3 |
| 2022-04-10 14:30:0010.04.2022 | Thun Tigers | 35 – 20 | Winterthur Warriors | NLA | 3 |
| 2022-04-10 14:30:0010.04.2022 | Basel Gladiators | 15 – 34 | Calanda Broncos | NLA | 3 |
| 2022-04-10 14:30:0010.04.2022 | St. Gallen Bears | 17 – 0 | Fribourg Cardinals | NLB | 3 |
| 2022-04-16 14:30:0016.04.2022 | Basel Gladiators | 14 – 30 | Geneva Seahawks | U19 Elite | 4 |
| 2022-04-16 18:00:0016.04.2022 | Basel Gladiators | 3 – 31 | Bern Grizzlies | NLA | 4 |
| 2022-04-16 18:00:0016.04.2022 | Langenthal Invaders | 46 – 7 | Neuchatel Knights | NLC | 4 |
| 2022-04-16 18:00:0016.04.2022 | LUCAF Owls | 7 – 0 | Orks | NLC | 4 |
| 2022-04-16 18:00:0016.04.2022 | Zofingen Cheetahs | 0 – 56 | Schaffhausen Sharks | NLC | 4 |
| 2022-04-17 14:00:0017.04.2022 | Fribourg Cardinals | 21 – 33 | Geneva Whoppers | NLB | 4 |
| 2022-04-17 14:00:0017.04.2022 | Morges Bandits | 47 – 6 | Niederbipp Ducks | NLC | 4 |
| 2022-04-18 11:00:0018.04.2022 | Calanda Broncos | 57 – 12 | Winterthur Warriors | U19 Elite | 4 |
| 2022-04-18 11:00:0018.04.2022 | St. Gallen Bears | 7 – 60 | Zurich Renegades | U19 Elite | 4 |
| 2022-04-18 11:00:0018.04.2022 | Thun Tigers | 52 – 7 | Argovia Pirates | U19 Elite | 4 |
| 2022-04-18 14:00:0018.04.2022 | Bienna Jets | 12 – 22 | Argovia Pirates | NLB | 4 |
| 2022-04-18 14:30:0018.04.2022 | Calanda Broncos | 34 – 6 | Winterthur Warriors | NLA | 4 |
| 2022-04-18 14:30:0018.04.2022 | Thun Tigers | 34 – 0 | Zurich Renegades | NLA | 4 |
| 2022-04-18 14:30:0018.04.2022 | St. Gallen Bears | 6 – 5 | Luzern Lions | NLB | 4 |
| 2022-04-23 00:00:0023.04.2022 | Belgrade SBB Vukovi | 21 – 35 | Vienna Danube Dragons | CEFL | – |
| 2022-04-23 00:00:0023.04.2022 | Towers | 25 – 56 | Örebro Black Knights | CEFL | – |
| 2022-04-23 00:00:0023.04.2022 | Dracs | 7 – 49 | Flash de La Courneuve | CEFL | – |
| 2022-04-23 00:00:0023.04.2022 | Budapest Wolves | 00:00:000:00 | Spartans | CEFL | – |
| 2022-04-23 14:30:0023.04.2022 | Zurich State Spartans | 14:30:00Abgesagt | Zofingen Cheetahs | NLC | 5 |
| 2022-04-23 18:00:0023.04.2022 | Langenthal Invaders | 67 – 6 | Niederbipp Ducks | NLC | 5 |
| 2022-04-23 18:00:0023.04.2022 | Neuchatel Knights | 12 – 5 | LUCAF Owls | NLC | 5 |
| 2022-04-24 11:00:0024.04.2022 | Bern Grizzlies | 18 – 20 | Winterthur Warriors | U19 Elite | 5 |
| 2022-04-24 11:00:0024.04.2022 | Geneva Seahawks | 36 – 22 | Zurich Renegades | U19 Elite | 5 |
| 2022-04-24 11:00:0024.04.2022 | St. Gallen Bears | 0 – 53 | Calanda Broncos | U19 Elite | 5 |
| 2022-04-24 11:00:0024.04.2022 | Lugano Rebels | 21 – 07 | Neuchatel Knights | U19 Challenge League | 5 |
| 2022-04-24 14:00:0024.04.2022 | Geneva Whoppers | 07 – 42 | Luzern Lions | NLB | 5 |
| 2022-04-24 14:00:0024.04.2022 | Dragons | 26 – 06 | Orks | NLC | 5 |
| 2022-04-24 14:00:0024.04.2022 | Lugano Rebels | 21 – 40 | Schaffhausen Sharks | NLC | 5 |
| 2022-04-24 14:30:0024.04.2022 | Bern Grizzlies | 24 – 7 | Thun Tigers | NLA | 5 |
| 2022-04-24 14:30:0024.04.2022 | Geneva Seahawks | 0 – 21 | Calanda Broncos | NLA | 5 |
| 2022-04-24 14:30:0024.04.2022 | St. Gallen Bears | 28 – 7 | Bienna Jets | NLB | 5 |
| 2022-04-30 13:00:0030.04.2022 | Bienna Jets | 13:00:00TBD | Lugano Rebels | U19 Challenge League | 6 |
| 2022-04-30 14:30:0030.04.2022 | Argovia Pirates | 14 – 36 | Geneva Seahawks | U19 Elite | 6 |
| 2022-04-30 14:30:0030.04.2022 | Winterthur Warriors | 12 – 39 | Basel Gladiators | U19 Elite | 6 |
| 2022-04-30 14:30:0030.04.2022 | Zurich State Spartans | 7 – 13 | Dragons | NLC | 6 |
| 2022-04-30 18:00:0030.04.2022 | Winterthur Warriors | 22 – 14 | Zurich Renegades | NLA | 6 |
| 2022-04-30 18:00:0030.04.2022 | Argovia Pirates | 7 – 3 | Fribourg Cardinals | NLB | 6 |
| 2022-05-01 11:00:0001.05.2022 | Bern Grizzlies | 33 – 12 | St. Gallen Bears | U19 Elite | 6 |
| 2022-05-01 11:00:0001.05.2022 | Thun Tigers | 39 – 43 | Calanda Broncos | U19 Elite | 6 |
| 2022-05-01 12:00:0001.05.2022 | Morges Bandits | 0 – 56 | Luzern Lions | U19 Challenge League | 6 |
| 2022-05-01 14:00:0001.05.2022 | Orks | 0 – 35 | Schaffhausen Sharks | NLC | 6 |
| 2022-05-01 14:00:0001.05.2022 | Morges Bandits | 21 – 35 | Langenthal Invaders | NLC | 6 |
| 2022-05-01 14:00:0001.05.2022 | Zofingen Cheetahs | 0 – 61 | Lugano Rebels | NLC | 6 |
| 2022-05-01 14:30:0001.05.2022 | Bern Grizzlies | 27 – 20 | Calanda Broncos | NLA | 6 |
| 2022-05-01 14:30:0001.05.2022 | Thun Tigers | 41 – 6 | Geneva Seahawks | NLA | 6 |
| 2022-05-07 00:00:0007.05.2022 | Schwäbisch Hall Unicorns | 58 – 7 | Örebro Black Knights | CEFL | – |
| 2022-05-07 14:00:0007.05.2022 | Neuchatel Knights | 0 – 41 | Bienna Jets | U19 Challenge League | 7 |
| 2022-05-07 14:30:0007.05.2022 | Calanda Broncos | 36 – 0 | Bern Grizzlies | U19 Elite | 7 |
| 2022-05-07 14:30:0007.05.2022 | St. Gallen Bears | 6 – 58 | Thun Tigers | U19 Elite | 7 |
| 2022-05-07 14:30:0007.05.2022 | St. Gallen Bears | 34 – 0 | Geneva Whoppers | NLB | 7 |
| 2022-05-07 18:00:0007.05.2022 | Calanda Broncos | 35 – 6 | Basel Gladiators | NLA | 7 |
| 2022-05-08 11:00:0008.05.2022 | Zurich Renegades | 20 – 27 | Basel Gladiators | U19 Elite | 7 |
| 2022-05-08 11:00:0008.05.2022 | Luzern Lions | 22 – 0 | Lugano Rebels | U19 Challenge League | 7 |
| 2022-05-08 12:00:0008.05.2022 | Geneva Seahawks | 50 – 0 | Winterthur Warriors | U19 Elite | 7 |
| 2022-05-08 14:00:0008.05.2022 | Fribourg Cardinals | 8 – 23 | Bienna Jets | NLB | 7 |
| 2022-05-08 14:00:0008.05.2022 | Luzern Lions | 9 – 14 | Argovia Pirates | NLB | 7 |
| 2022-05-08 14:00:0008.05.2022 | Dragons | 22 – 12 | Lugano Rebels | NLC | 7 |
| 2022-05-08 14:00:0008.05.2022 | Schaffhausen Sharks | 9 – 0 | Neuchatel Knights | NLC | 7 |
| 2022-05-08 14:00:0008.05.2022 | Zofingen Cheetahs | 6 – 28 | Niederbipp Ducks | NLC | 7 |
| 2022-05-08 14:30:0008.05.2022 | Zurich Renegades | 19 – 62 | Thun Tigers | NLA | 7 |
| 2022-05-08 15:30:0008.05.2022 | Geneva Seahawks | 21 – 7 | Winterthur Warriors | NLA | 7 |
| 2022-05-14 14:30:0014.05.2022 | Argovia Pirates | 15 – 0 | Bern Grizzlies | U19 Elite | 8 |
| 2022-05-14 15:00:0014.05.2022 | E-R Parma Panthers | 21 – 10 | Vienna Danube Dragons | CEFL | – |
| 2022-05-14 18:00:0014.05.2022 | Argovia Pirates | 15 – 27 | St. Gallen Bears | NLB | 8 |
| 2022-05-14 18:00:0014.05.2022 | Orks | 7 – 24 | Lugano Rebels | NLC | 8 |
| 2022-05-14 18:00:0014.05.2022 | Niederbipp Ducks | 14 – 15 | LUCAF Owls | NLC | 8 |
| 2022-05-14 18:00:0014.05.2022 | Black Panthers | 27 – 45 | Flash de La Courneuve | CEFL | – |
| 2022-05-14 18:00:0014.05.2022 | Calanda Broncos | 35 – 28 | Budapest Wolves | CEFL | – |
| 2022-05-15 11:00:0015.05.2022 | Zurich Renegades | 24 – 33 | Thun Tigers | U19 Elite | 8 |
| 2022-05-15 11:00:0015.05.2022 | Neuchatel Knights | 11:00:0011:00 | Morges Bandits | U19 Challenge League | 8 |
| 2022-05-15 14:00:0015.05.2022 | Geneva Whoppers | 18 – 25 | Bienna Jets | NLB | 8 |
| 2022-05-15 14:00:0015.05.2022 | Luzern Lions | 21 – 0 | Fribourg Cardinals | NLB | 8 |
| 2022-05-15 14:00:0015.05.2022 | Neuchatel Knights | 40 – 23 | Morges Bandits | NLC | 8 |
| 2022-05-15 14:00:0015.05.2022 | Schaffhausen Sharks | 17 – 03 | Zurich State Spartans | NLC | 8 |
| 2022-05-15 14:00:0015.05.2022 | Zofingen Cheetahs | 0 – 50 | Langenthal Invaders | NLC | 8 |
| 2022-05-15 14:30:0015.05.2022 | Zurich Renegades | 0 – 40 | Basel Gladiators | NLA | 8 |
| 2022-05-21 14:30:0021.05.2022 | Basel Gladiators | 52 – 7 | St. Gallen Bears | U19 Elite | 9 |
| 2022-05-21 15:00:0021.05.2022 | LUCAF Owls | 0 – 32 | Schaffhausen Sharks | NLC | 9 |
| 2022-05-21 18:00:0021.05.2022 | Basel Gladiators | 24 – 7 | Geneva Seahawks | NLA | 9 |
| 2022-05-22 11:00:0022.05.2022 | Bern Grizzlies | 6 – 41 | Thun Tigers | U19 Elite | 9 |
| 2022-05-22 11:00:0022.05.2022 | Zurich Renegades | 23 – 15 | Calanda Broncos | U19 Elite | 9 |
| 2022-05-22 11:00:0022.05.2022 | Lugano Rebels | 11:00:0011:00 | Morges Bandits | U19 Challenge League | 9 |
| 2022-05-22 11:00:0022.05.2022 | Neuchatel Knights | 0 – 14 | Luzern Lions | U19 Challenge League | 9 |
| 2022-05-22 14:00:0022.05.2022 | Bienna Jets | 7 – 28 | Luzern Lions | NLB | 9 |
| 2022-05-22 14:00:0022.05.2022 | Fribourg Cardinals | 6 – 12 | St. Gallen Bears | NLB | 9 |
| 2022-05-22 14:00:0022.05.2022 | Geneva Whoppers | 12 – 23 | Argovia Pirates | NLB | 9 |
| 2022-05-22 14:00:0022.05.2022 | Lugano Rebels | 22 – 25 | Morges Bandits | NLC | 9 |
| 2022-05-22 14:00:0022.05.2022 | Neuchatel Knights | 15 – 22 | Dragons | NLC | 9 |
| 2022-05-22 14:00:0022.05.2022 | Niederbipp Ducks | 21 – 35 | Zurich State Spartans | NLC | 9 |
| 2022-05-22 14:30:0022.05.2022 | Bern Grizzlies | 69 – 7 | Winterthur Warriors | NLA | 9 |
| 2022-05-22 14:30:0022.05.2022 | Zurich Renegades | 20 – 44 | Calanda Broncos | NLA | 9 |
| 2022-05-28 14:00:0028.05.2022 | St. Gallen Bears | 28 – 7 | Argovia Pirates | NLB | 10 |
| 2022-05-28 14:30:0028.05.2022 | Calanda Broncos | 47 – 26 | Geneva Seahawks | U19 Elite | 10 |
| 2022-05-28 14:30:0028.05.2022 | Thun Tigers | 42 – 21 | Basel Gladiators | U19 Elite | 10 |
| 2022-05-28 14:30:0028.05.2022 | Winterthur Warriors | 34 – 14 | St. Gallen Bears | U19 Elite | 10 |
| 2022-05-28 15:00:0028.05.2022 | Bienna Jets | 15:00:00Abgesagt | Morges Bandits | U19 Challenge League | 5 |
| 2022-05-28 18:00:0028.05.2022 | Calanda Broncos | 21 – 14 | Geneva Seahawks | NLA | 10 |
| 2022-05-28 18:00:0028.05.2022 | Thun Tigers | 20 – 24 | Basel Gladiators | NLA | 10 |
| 2022-05-28 18:00:0028.05.2022 | Langenthal Invaders | 55 – 7 | Orks | NLC | 10 |
| 2022-05-29 11:00:0029.05.2022 | Zurich Renegades | 33 – 8 | Argovia Pirates | U19 Elite | 10 |
| 2022-05-29 14:00:0029.05.2022 | Fribourg Cardinals | 12 – 20 | Luzern Lions | NLB | 10 |
| 2022-05-29 14:00:0029.05.2022 | Lugano Rebels | 62 – 0 | Niederbipp Ducks | NLC | 10 |
| 2022-05-29 14:00:0029.05.2022 | Morges Bandits | 53 – 6 | Zofingen Cheetahs | NLC | 10 |
| 2022-05-29 14:30:0029.05.2022 | Zurich Renegades | 12 – 38 | Winterthur Warriors | NLA | 10 |
| 2022-05-29 14:30:0029.05.2022 | Zurich State Spartans | 6 – 13 | LUCAF Owls | NLC | 10 |
| 2022-06-04 00:00:0004.06.2022 | Bye Week | 00:00:000:00 | Spielplan | U19 Challenge League | 11 |
| 2022-06-04 14:30:0004.06.2022 | Argovia Pirates | 12 – 44 | Calanda Broncos | U19 Elite | 11 |
| 2022-06-04 14:30:0004.06.2022 | Basel Gladiators | 27 – 8 | Bern Grizzlies | U19 Elite | 11 |
| 2022-06-04 14:30:0004.06.2022 | Geneva Seahawks | 32 – 44 | Thun Tigers | U19 Elite | 11 |
| 2022-06-04 14:30:0004.06.2022 | Winterthur Warriors | 26 – 43 | Zurich Renegades | U19 Elite | 11 |
| 2022-06-04 18:00:0004.06.2022 | Geneva Seahawks | 0 – 55 | Bern Grizzlies | NLA | 11 |
| 2022-06-04 18:00:0004.06.2022 | Winterthur Warriors | 21 – 24 | Thun Tigers | NLA | 11 |
| 2022-06-04 18:00:0004.06.2022 | Basel Gladiators | 28 – 15 | Zurich Renegades | NLA | 11 |
| 2022-06-04 18:00:0004.06.2022 | Argovia Pirates | 10 – 42 | Bienna Jets | NLB | 11 |
| 2022-06-04 18:00:0004.06.2022 | Geneva Whoppers | 0 – 6 | Fribourg Cardinals | NLB | 11 |
| 2022-06-04 18:00:0004.06.2022 | Cologne Centurions | 40 – 38 | Rams | ELF | 11 |
| 2022-06-04 18:00:0904.06.2022 | Calanda Broncos | 9 – 21 | E-R Parma Panthers | CEFL | – |
| 2022-06-05 14:00:0005.06.2022 | LUCAF Owls | 14:00:00Abgesagt | Zofingen Cheetahs | NLC | 11 |
| 2022-06-05 14:00:0005.06.2022 | Lugano Rebels | 48 – 23 | Zurich State Spartans | NLC | 11 |
| 2022-06-05 14:00:0005.06.2022 | Morges Bandits | 0 – 13 | Dragons | NLC | 11 |
| 2022-06-05 14:00:0005.06.2022 | Neuchatel Knights | 16 – 19 | Orks | NLC | 11 |
| 2022-06-05 15:00:0005.06.2022 | Frankfurt Galaxy | 26 – 29 | Rhein Fire | ELF | 11 |
| 2022-06-05 15:00:0005.06.2022 | Stuttgart Surge | 9 – 38 | Barcelona Dragons | ELF | 11 |
| 2022-06-05 15:00:0005.06.2022 | Panthers | 34 – 27 | Leipzig Kings | ELF | 11 |
| 2022-06-05 15:00:0005.06.2022 | Hamburg Sea Devils | 43 – 18 | Berlin Thunder | ELF | 11 |
| 2022-06-05 15:00:0005.06.2022 | Raiders | 23 – 29 | Vikings | ELF | 11 |
| 2022-06-11 00:00:0011.06.2022 | Spielplan | 00:00:000:00 | | U19 Challenge League | 12 |
| 2022-06-11 14:30:0011.06.2022 | Argovia Pirates | 8 – 23 | St. Gallen Bears | U19 Elite | 12 |
| 2022-06-11 15:00:0011.06.2022 | Cologne Centurions | 49 – 46 | Raiders | ELF | 12 |
| 2022-06-11 15:00:0011.06.2022 | Berlin Thunder | 41 – 7 | Rams | ELF | 12 |
| 2022-06-11 18:00:0011.06.2022 | Calanda Broncos | 23 – 30 | Bern Grizzlies | NLA | 12 |
| 2022-06-11 18:00:0011.06.2022 | Winterthur Warriors | 13 – 21 | Basel Gladiators | NLA | 12 |
| 2022-06-11 18:00:0011.06.2022 | Dragons | 20 – 24 | Langenthal Invaders | NLC | 12 |
| 2022-06-11 18:00:0011.06.2022 | Orks | 19 – 12 | Zurich State Spartans | NLC | 12 |
| 2022-06-11 18:00:0011.06.2022 | Niederbipp Ducks | 3 – 35 | Schaffhausen Sharks | NLC | 12 |
| 2022-06-12 11:00:1412.06.2022 | Luzern Lions | 32 – 0 | Lugano Rebels | U19 Challenge League | 12 |
| 2022-06-12 11:00:1812.06.2022 | Bienna Jets | 39 – 6 | Neuchatel Knights | U19 Challenge League | 12 |
| 2022-06-12 14:00:0012.06.2022 | Bienna Jets | 7 – 10 | St. Gallen Bears | NLB | 12 |
| 2022-06-12 14:00:0012.06.2022 | Fribourg Cardinals | 6 – 21 | Argovia Pirates | NLB | 12 |
| 2022-06-12 14:00:0012.06.2022 | Luzern Lions | 23 – 8 | Geneva Whoppers | NLB | 12 |
| 2022-06-12 14:00:0012.06.2022 | Leipzig Kings | 17 – 28 | Rhein Fire | ELF | 12 |
| 2022-06-12 14:00:0012.06.2022 | LUCAF Owls | 0 – 50 | Morges Bandits | NLC | 12 |
| 2022-06-12 14:30:0012.06.2022 | Zurich Renegades | 37 – 6 | Geneva Seahawks | NLA | 12 |
| 2022-06-12 15:00:0012.06.2022 | Stuttgart Surge | 25 – 28 | Panthers | ELF | 12 |
| 2022-06-12 15:00:0012.06.2022 | Hamburg Sea Devils | 21 – 24 | Barcelona Dragons | ELF | 12 |
| 2022-06-12 15:00:0012.06.2022 | Vikings | 30 – 10 | Frankfurt Galaxy | ELF | 12 |
| 2022-06-18 14:00:0018.06.2022 | Orks | 50 – 0 | Zofingen Cheetahs | NLC | 13 |
| 2022-06-18 18:00:0018.06.2022 | Geneva Seahawks | 3 – 14 | Basel Gladiators | NLA | 13 |
| 2022-06-18 18:00:0018.06.2022 | Winterthur Warriors | 27 – 28 | Calanda Broncos | NLA | 13 |
| 2022-06-18 18:00:0018.06.2022 | Argovia Pirates | 0 – 21 | Luzern Lions | NLB | 13 |
| 2022-06-18 18:00:0018.06.2022 | Leipzig Kings | 0 – 14 | Hamburg Sea Devils | ELF | 13 |
| 2022-06-18 18:00:0018.06.2022 | Barcelona Dragons | 34 – 32 | Cologne Centurions | ELF | 13 |
| 2022-06-18 18:00:0018.06.2022 | Langenthal Invaders | 28 – 19 | LUCAF Owls | NLC | 13 |
| 2022-06-19 11:00:2519.06.2022 | Bienna Jets | 20 – 12 | Luzern Lions | U19 Challenge League | 13 |
| 2022-06-19 14:00:0019.06.2022 | Thun Tigers | 6 – 36 | Bern Grizzlies | NLA | 13 |
| 2022-06-19 14:00:0019.06.2022 | Geneva Whoppers | 0 – 29 | St. Gallen Bears | NLB | 13 |
| 2022-06-19 14:00:0019.06.2022 | Lugano Rebels | 21 – 7 | Neuchatel Knights | NLC | 13 |
| 2022-06-19 14:00:0019.06.2022 | Schaffhausen Sharks | 20 – 14 | Dragons | NLC | 13 |
| 2022-06-19 14:30:0019.06.2022 | Bienna Jets | 37 – 0 | Fribourg Cardinals | NLB | 13 |
| 2022-06-19 15:00:0019.06.2022 | Rhein Fire | 42 – 12 | Rams | ELF | 13 |
| 2022-06-19 15:00:0019.06.2022 | Vikings | 42 – 13 | Stuttgart Surge | ELF | 13 |
| 2022-06-19 15:00:0019.06.2022 | Frankfurt Galaxy | 47 – 13 | Panthers | ELF | 13 |
| 2022-06-19 15:00:0019.06.2022 | Raiders | 28 – 16 | Berlin Thunder | ELF | 13 |
| 2022-06-25 18:00:0025.06.2022 | Cologne Centurions | 12 – 48 | Frankfurt Galaxy | ELF | 14 |
| 2022-06-25 18:00:0025.06.2022 | Rams | 0 – 49 | Vikings | ELF | 14 |
| 2022-06-25 18:00:0025.06.2022 | Orks | 48 – 0 | Niederbipp Ducks | NLC | 14 |
| 2022-06-26 14:00:0026.06.2022 | Bern Grizzlies | 35 – 0 | Zurich Renegades | NLA | 14 |
| 2022-06-26 14:00:0026.06.2022 | Bienna Jets | 27 – 6 | Geneva Whoppers | NLB | 14 |
| 2022-06-26 14:00:0026.06.2022 | Luzern Lions | 9 – 2 | St. Gallen Bears | NLB | 14 |
| 2022-06-26 14:00:0026.06.2022 | Dragons | 25 – 19 | LUCAF Owls | NLC | 14 |
| 2022-06-26 14:00:0026.06.2022 | Langenthal Invaders | 48 – 6 | Lugano Rebels | NLC | 14 |
| 2022-06-26 14:30:0026.06.2022 | Zurich State Spartans | 20 – 0 | Morges Bandits | NLC | 14 |
| 2022-06-26 15:00:0026.06.2022 | Panthers | 23 – 26 | Hamburg Sea Devils | ELF | 14 |
| 2022-06-26 15:00:0026.06.2022 | Berlin Thunder | 15 – 19 | Leipzig Kings | ELF | 14 |
| 2022-06-26 15:00:0026.06.2022 | Raiders | 33 – 0 | Stuttgart Surge | ELF | 14 |
| 2022-06-26 15:00:0026.06.2022 | Rhein Fire | 13 – 17 | Barcelona Dragons | ELF | 14 |
| 2022-06-26 18:00:0026.06.2022 | Basel Gladiators | 34 – 6 | Thun Tigers | NLA | 14 |
| 2022-07-02 15:00:0002.07.2022 | Cologne Centurions | 7 – 34 | Berlin Thunder | ELF | 15 |
| 2022-07-02 18:00:0002.07.2022 | Argovia Pirates | 33 – 0 | Geneva Whoppers | NLB | 15 |
| 2022-07-02 18:00:0002.07.2022 | Barcelona Dragons | 41 – 7 | Rams | ELF | 15 |
| 2022-07-03 14:00:0003.07.2022 | Schaffhausen Sharks | 42 – 7 | Morges Bandits | NLC | 15 |
| 2022-07-03 14:00:0003.07.2022 | Zofingen Cheetahs | 0 – 42 | Neuchatel Knights | NLC | 15 |
| 2022-07-03 15:00:0003.07.2022 | Hamburg Sea Devils | 42 – 15 | Rhein Fire | ELF | 15 |
| 2022-07-03 15:00:0003.07.2022 | Vikings | 30 – 6 | Panthers | ELF | 15 |
| 2022-07-03 15:00:0003.07.2022 | Leipzig Kings | 28 – 22 | Stuttgart Surge | ELF | 15 |
| 2022-07-03 15:00:0003.07.2022 | Raiders | 23 – 17 | Frankfurt Galaxy | ELF | 15 |
| 2022-07-09 15:00:0009.07.2022 | Rams | 0 – 70 | Hamburg Sea Devils | ELF | 16 |
| 2022-07-09 18:00:0009.07.2022 | Barcelona Dragons | 20 – 27 | Vikings | ELF | 16 |
| 2022-07-10 15:00:0010.07.2022 | Raiders | 37 – 6 | Leipzig Kings | ELF | 16 |
| 2022-07-10 15:00:0010.07.2022 | Berlin Thunder | 31 – 25 | Panthers | ELF | 16 |
| 2022-07-10 15:00:0010.07.2022 | Stuttgart Surge | 20 – 26 | Frankfurt Galaxy | ELF | 16 |
| 2022-07-10 15:00:0010.07.2022 | Rhein Fire | 17 – 3 | Cologne Centurions | ELF | 16 |
| 2022-07-17 15:00:0017.07.2022 | Leipzig Kings | 22 – 33 | Berlin Thunder | ELF | 17 |
| 2022-07-17 15:00:0017.07.2022 | Frankfurt Galaxy | 46 – 14 | Cologne Centurions | ELF | 17 |
| 2022-07-17 15:00:0017.07.2022 | Panthers | 34 – 0 | Stuttgart Surge | ELF | 17 |
| 2022-07-23 15:00:0023.07.2022 | Rams | 22 – 19 | Barcelona Dragons | ELF | 18 |
| 2022-07-24 15:00:0024.07.2022 | Rhein Fire | 16 – 40 | Hamburg Sea Devils | ELF | 18 |
| 2022-07-24 15:00:0024.07.2022 | Vikings | 29 – 13 | Raiders | ELF | 18 |
| 2022-07-30 15:00:0030.07.2022 | Stuttgart Surge | 0 – 41 | Vikings | ELF | 19 |
| 2022-07-30 18:00:0030.07.2022 | Barcelona Dragons | 32 – 23 | Rhein Fire | ELF | 19 |
| 2022-07-31 15:00:0031.07.2022 | Panthers | 29 – 30 | Frankfurt Galaxy | ELF | 19 |
| 2022-07-31 15:00:0031.07.2022 | Hamburg Sea Devils | 29 – 26 | Rams | ELF | 19 |
| 2022-07-31 15:00:0031.07.2022 | Leipzig Kings | 14 – 56 | Raiders | ELF | 19 |
| 2022-07-31 15:00:0031.07.2022 | Berlin Thunder | 39 – 29 | Cologne Centurions | ELF | 19 |
| 2022-08-13 12:00:0013.08.2022 | Cologne Centurions | 15 – 37 | Barcelona Dragons | ELF | 21 |
| 2022-08-13 12:00:0013.08.2022 | Rams | 32 – 50 | Rhein Fire | ELF | 21 |
| 2022-08-14 12:00:0014.08.2022 | Panthers | 12 – 29 | Berlin Thunder | ELF | 21 |
| 2022-08-14 12:00:0014.08.2022 | Hamburg Sea Devils | 59 – 0 | Leipzig Kings | ELF | 21 |
| 2022-08-14 12:00:0014.08.2022 | Frankfurt Galaxy | 42 – 8 | Vikings | ELF | 21 |
| 2022-08-14 12:00:0014.08.2022 | Raiders | 44 – 3 | Stuttgart Surge | ELF | 21 |
| 2022-08-20 12:00:0020.08.2022 | Barcelona Dragons | 62 – 8 | Stuttgart Surge | ELF | 22 |
| 2022-08-20 15:00:0020.08.2022 | Calanda Broncos | 42 – 6 | Winterthur Warriors | U16 | 1 |
| 2022-08-21 12:00:0021.08.2022 | Berlin Thunder | 17 – 39 | Hamburg Sea Devils | ELF | 22 |
| 2022-08-21 12:00:0021.08.2022 | Leipzig Kings | 37 – 41 | Panthers | ELF | 22 |
| 2022-08-21 12:00:0021.08.2022 | Rhein Fire | 23 – 21 | Frankfurt Galaxy | ELF | 22 |
| 2022-08-21 12:00:0021.08.2022 | Vikings | 37 – 22 | Rams | ELF | 22 |
| 2022-08-21 12:00:0021.08.2022 | Raiders | 45 – 20 | Cologne Centurions | ELF | 22 |
| 2022-08-21 14:00:0021.08.2022 | Thun Tigers | 56 – 8 | Zurich Renegades | U16 | 1 |
| 2022-08-21 14:30:0021.08.2022 | Bern Grizzlies | 13 – 12 | Basel Gladiators | U16 | 1 |
| 2022-08-27 12:00:0027.08.2022 | Cologne Centurions | 37 – 59 | Rhein Fire | ELF | 23 |
| 2022-08-27 12:00:0027.08.2022 | Rams | 14 – 38 | Berlin Thunder | ELF | 23 |
| 2022-08-27 15:00:0027.08.2022 | Calanda Broncos | 16 – 6 | Thun Tigers | U16 | 2 |
| 2022-08-28 12:00:0028.08.2022 | Vikings | 24 – 18 | Barcelona Dragons | ELF | 23 |
| 2022-08-28 12:00:0028.08.2022 | Stuttgart Surge | 0 – 38 | Leipzig Kings | ELF | 23 |
| 2022-08-28 12:00:0028.08.2022 | Frankfurt Galaxy | 36 – 33 | Raiders | ELF | 23 |
| 2022-08-28 12:00:0028.08.2022 | Hamburg Sea Devils | 17 – 0 | Panthers | ELF | 23 |
| 2022-08-28 14:00:0028.08.2022 | Winterthur Warriors | 16 – 0 | Bern Grizzlies | U16 | 2 |
| 2022-08-28 14:00:0028.08.2022 | Zurich Renegades | 44 – 14 | Basel Gladiators | U16 | 2 |
| 2022-09-03 12:00:0003.09.2022 | Rams | 30 – 43 | Cologne Centurions | ELF | 24 |
| 2022-09-03 12:00:0003.09.2022 | Barcelona Dragons | 21 – 24 | Hamburg Sea Devils | ELF | 24 |
| 2022-09-04 12:00:0004.09.2022 | Berlin Thunder | 10 – 37 | Raiders | ELF | 24 |
| 2022-09-04 12:00:0004.09.2022 | Rhein Fire | 31 – 34 | Leipzig Kings | ELF | 24 |
| 2022-09-04 12:00:0004.09.2022 | Panthers | 42 – 6 | Vikings | ELF | 24 |
| 2022-09-04 12:00:0004.09.2022 | Frankfurt Galaxy | 37 – 13 | Stuttgart Surge | ELF | 24 |
| 2022-09-04 14:00:0004.09.2022 | Basel Gladiators | 0 – 34 | Winterthur Warriors | U16 | 3 |
| 2022-09-04 14:00:0004.09.2022 | Thun Tigers | 42 – 0 | Bern Grizzlies | U16 | 3 |
| 2022-09-04 14:00:0004.09.2022 | Zurich Renegades | 6 – 40 | Calanda Broncos | U16 | 3 |
| 2022-09-09 02:20:0009.09.2022 | Rams | 10 – 31 | Bills | NFL | 1 |
| 2022-09-10 15:00:0010.09.2022 | Bern Grizzlies | 0 – 32 | Calanda Broncos | U16 | 4 |
| 2022-09-11 14:00:0011.09.2022 | Basel Gladiators | 8 – 76 | Thun Tigers | U16 | 4 |
| 2022-09-11 14:00:0011.09.2022 | Winterthur Warriors | 22 – 38 | Zurich Renegades | U16 | 4 |
| 2022-09-11 19:00:0011.09.2022 | Falcons | 26 – 27 | Saints | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Panthers | 24 – 26 | Browns | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Bears | 19 – 10 | 49ers | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Bengals | 20 – 23 | Steelers | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Lions | 35 – 38 | Eagles | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Texans | 20 – 20 | Colts | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Dolphins | 20 – 7 | Patriots | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Jets | 9 – 24 | Ravens | NFL | 1 |
| 2022-09-11 19:00:0011.09.2022 | Washington | 28 – 22 | Jaguars | NFL | 1 |
| 2022-09-11 22:25:0011.09.2022 | Arizona Cardinals | 22:25:0022:25 | Chiefs | NFL | 1 |
| 2022-09-11 22:25:0011.09.2022 | Chargers | 24 – 19 | Raiders | NFL | 1 |
| 2022-09-11 22:25:0011.09.2022 | Vikings | 23 – 7 | Packers | NFL | 1 |
| 2022-09-11 22:25:0011.09.2022 | Titans | 20 – 21 | Giants | NFL | 1 |
| 2022-09-12 02:20:0012.09.2022 | Cowboys | 3 – 19 | Buccaneers | NFL | 1 |
| 2022-09-13 02:15:0013.09.2022 | Seahawks | 17 – 16 | Broncos | NFL | 1 |
| 2022-09-16 02:15:0016.09.2022 | Chiefs | 27 – 24 | Chargers | NFL | 2 |
| 2022-09-17 00:00:0017.09.2022 | Bye Week | 00:00:000:00 | Bye Week | U16 | 5 |
| 2022-09-18 19:00:0018.09.2022 | Ravens | 38 – 42 | Dolphins | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Browns | 30 – 31 | Jets | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Lions | 36 – 27 | Washington | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Jaguars | 24 – 0 | Colts | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Saints | 10 – 20 | Buccaneers | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Giants | 19 – 16 | Panthers | NFL | 2 |
| 2022-09-18 19:00:0018.09.2022 | Steelers | 14 – 17 | Patriots | NFL | 2 |
| 2022-09-18 22:05:0018.09.2022 | Rams | 31 – 27 | Falcons | NFL | 2 |
| 2022-09-18 22:05:0018.09.2022 | 49ers | 27 – 7 | Seahawks | NFL | 2 |
| 2022-09-18 22:25:0018.09.2022 | Cowboys | 20 – 17 | Bengals | NFL | 2 |
| 2022-09-18 22:25:0018.09.2022 | Broncos | 16 – 9 | Texans | NFL | 2 |
| 2022-09-18 22:25:0018.09.2022 | Raiders | 23 – 29 | Arizona Cardinals | NFL | 2 |
| 2022-09-19 02:20:0019.09.2022 | Packers | 27 – 10 | Bears | NFL | 2 |
| 2022-09-20 01:15:0020.09.2022 | Bills | 41 – 7 | Titans | NFL | 2 |
| 2022-09-20 02:30:0020.09.2022 | Eagles | 24 – 7 | Vikings | NFL | 2 |
| 2022-09-23 02:15:0023.09.2022 | Browns | 29 – 17 | Steelers | NFL | 3 |
| 2022-09-24 15:00:0024.09.2022 | Calanda Broncos | 44 – 14 | Basel Gladiators | U16 | 6 |
| 2022-09-25 12:00:3625.09.2022 | Hamburg Sea Devils | 15 – 27 | Vikings | ELF | – |
| 2022-09-25 14:00:0025.09.2022 | Thun Tigers | 6 – 28 | Winterthur Warriors | U16 | 6 |
| 2022-09-25 14:00:0025.09.2022 | Zurich Renegades | 26 – 0 | Bern Grizzlies | U16 | 6 |
| 2022-09-25 19:00:0025.09.2022 | Panthers | 22 – 14 | Saints | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Bears | 23 – 20 | Texans | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Colts | 20 – 17 | Chiefs | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Dolphins | 21 – 19 | Bills | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Vikings | 28 – 24 | Lions | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Patriots | 26 – 37 | Ravens | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Jets | 12 – 27 | Bengals | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Titans | 24 – 22 | Raiders | NFL | 3 |
| 2022-09-25 19:00:0025.09.2022 | Washington | 8 – 24 | Eagles | NFL | 3 |
| 2022-09-25 22:05:0025.09.2022 | Chargers | 10 – 38 | Jaguars | NFL | 3 |
| 2022-09-25 22:25:0025.09.2022 | Arizona Cardinals | 12 – 20 | Rams | NFL | 3 |
| 2022-09-25 22:25:0025.09.2022 | Seahawks | 23 – 27 | Falcons | NFL | 3 |
| 2022-09-25 22:25:0025.09.2022 | Buccaneers | 12 – 14 | Packers | NFL | 3 |
| 2022-09-26 02:20:0026.09.2022 | Broncos | 11 – 10 | 49ers | NFL | 3 |
| 2022-09-27 02:15:0027.09.2022 | Giants | 02:15:002:15 | Cowboys | NFL | 3 |
| 2022-09-30 02:15:0030.09.2022 | Bengals | 02:15:002:15 | Dolphins | NFL | 4 |
| 2022-10-01 15:00:0001.10.2022 | Bern Grizzlies | 0 – 34 | Thun Tigers | U16 | 7 |
| 2022-10-02 14:00:0002.10.2022 | Basel Gladiators | 14:00:0014:00 | Zurich Renegades | U16 | 7 |
| 2022-10-02 14:00:0002.10.2022 | Winterthur Warriors | 14:00:0014:00 | Calanda Broncos | U16 | 7 |
| 2022-10-02 15:30:0002.10.2022 | Saints | 15:30:0015:30 | Vikings | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Falcons | 19:00:0019:00 | Browns | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Ravens | 19:00:0019:00 | Bills | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Cowboys | 19:00:0019:00 | Washington | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Lions | 19:00:0019:00 | Seahawks | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Texans | 19:00:0019:00 | Chargers | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Colts | 19:00:0019:00 | Titans | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Giants | 19:00:0019:00 | Bears | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Eagles | 19:00:0019:00 | Jaguars | NFL | 4 |
| 2022-10-02 19:00:0002.10.2022 | Steelers | 19:00:0019:00 | Jets | NFL | 4 |
| 2022-10-02 22:05:0002.10.2022 | Panthers | 22:05:0022:05 | Arizona Cardinals | NFL | 4 |
| 2022-10-02 22:25:0002.10.2022 | Packers | 22:25:0022:25 | Patriots | NFL | 4 |
| 2022-10-02 22:25:0002.10.2022 | Raiders | 22:25:0022:25 | Broncos | NFL | 4 |
| 2022-10-03 02:20:0003.10.2022 | Buccaneers | 02:20:002:20 | Chiefs | NFL | 4 |
| 2022-10-04 02:15:0004.10.2022 | 49ers | 02:15:002:15 | Rams | NFL | 4 |
| 2022-10-07 02:15:0007.10.2022 | Broncos | 02:15:002:15 | Colts | NFL | 5 |
| 2022-10-08 00:00:0008.10.2022 | Bye Week | 00:00:000:00 | Bye Week | U16 | 8 |
| 2022-10-09 15:30:0009.10.2022 | Packers | 15:30:0015:30 | Giants | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Bills | 19:00:0019:00 | Steelers | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Browns | 19:00:0019:00 | Chargers | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Jaguars | 19:00:0019:00 | Texans | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Vikings | 19:00:0019:00 | Bears | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Patriots | 19:00:0019:00 | Lions | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Saints | 19:00:0019:00 | Seahawks | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Jets | 19:00:0019:00 | Dolphins | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Buccaneers | 19:00:0019:00 | Falcons | NFL | 5 |
| 2022-10-09 19:00:0009.10.2022 | Washington | 19:00:0019:00 | Titans | NFL | 5 |
| 2022-10-09 22:05:0009.10.2022 | Panthers | 22:05:0022:05 | 49ers | NFL | 5 |
| 2022-10-09 22:25:0009.10.2022 | Arizona Cardinals | 22:25:0022:25 | Eagles | NFL | 5 |
| 2022-10-09 22:25:0009.10.2022 | Rams | 22:25:0022:25 | Cowboys | NFL | 5 |
| 2022-10-10 02:20:0010.10.2022 | Ravens | 02:20:002:20 | Bengals | NFL | 5 |
| 2022-10-11 02:15:0011.10.2022 | Chiefs | 02:15:002:15 | Raiders | NFL | 5 |
| 2022-10-14 02:15:0014.10.2022 | Bears | 02:15:002:15 | Washington | NFL | 6 |
| 2022-10-15 00:00:0015.10.2022 | Semi-Finals | 00:00:000:00 | Semi-Finals | U16 | 9 |
| 2022-10-16 19:00:0016.10.2022 | Falcons | 19:00:0019:00 | 49ers | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Browns | 19:00:0019:00 | Patriots | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Packers | 19:00:0019:00 | Jets | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Colts | 19:00:0019:00 | Jaguars | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Dolphins | 19:00:0019:00 | Vikings | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Saints | 19:00:0019:00 | Bengals | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Giants | 19:00:0019:00 | Ravens | NFL | 6 |
| 2022-10-16 19:00:0016.10.2022 | Steelers | 19:00:0019:00 | Buccaneers | NFL | 6 |
| 2022-10-16 22:05:0016.10.2022 | Rams | 22:05:0022:05 | Panthers | NFL | 6 |
| 2022-10-16 22:05:0016.10.2022 | Seahawks | 22:05:0022:05 | Arizona Cardinals | NFL | 6 |
| 2022-10-16 22:25:0016.10.2022 | Chiefs | 22:25:0022:25 | Bills | NFL | 6 |
| 2022-10-17 02:20:0017.10.2022 | Eagles | 02:20:002:20 | Cowboys | NFL | 6 |
| 2022-10-18 02:15:0018.10.2022 | Chargers | 02:15:002:15 | Broncos | NFL | 6 |
| 2022-10-21 02:15:0021.10.2022 | Arizona Cardinals | 02:15:002:15 | Saints | NFL | 7 |
| 2022-10-22 00:00:0022.10.2022 | Finals | 00:00:000:00 | Finals | U16 | 10 |
| 2022-10-23 19:00:0023.10.2022 | Ravens | 19:00:0019:00 | Browns | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Panthers | 19:00:0019:00 | Buccaneers | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Bengals | 19:00:0019:00 | Falcons | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Cowboys | 19:00:0019:00 | Lions | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Jaguars | 19:00:0019:00 | Giants | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Titans | 19:00:0019:00 | Colts | NFL | 7 |
| 2022-10-23 19:00:0023.10.2022 | Washington | 19:00:0019:00 | Packers | NFL | 7 |
| 2022-10-23 22:05:0023.10.2022 | Broncos | 22:05:0022:05 | Jets | NFL | 7 |
| 2022-10-23 22:05:0023.10.2022 | Raiders | 22:05:0022:05 | Texans | NFL | 7 |
| 2022-10-23 22:25:0023.10.2022 | Chargers | 22:25:0022:25 | Seahawks | NFL | 7 |
| 2022-10-23 22:25:0023.10.2022 | 49ers | 22:25:0022:25 | Chiefs | NFL | 7 |
| 2022-10-24 02:20:0024.10.2022 | Dolphins | 02:20:002:20 | Steelers | NFL | 7 |
| 2022-10-25 02:15:0025.10.2022 | Patriots | 02:15:002:15 | Bears | NFL | 7 |
| 2022-10-28 02:15:0028.10.2022 | Buccaneers | 02:15:002:15 | Ravens | NFL | 8 |
| 2022-10-30 14:30:0030.10.2022 | Jaguars | 14:30:0014:30 | Broncos | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Falcons | 18:00:0018:00 | Panthers | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Cowboys | 18:00:0018:00 | Bears | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Lions | 18:00:0018:00 | Dolphins | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Vikings | 18:00:0018:00 | Arizona Cardinals | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Saints | 18:00:0018:00 | Raiders | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Jets | 18:00:0018:00 | Patriots | NFL | 8 |
| 2022-10-30 18:00:0030.10.2022 | Eagles | 18:00:0018:00 | Steelers | NFL | 8 |
| 2022-10-30 21:05:0030.10.2022 | Texans | 21:05:0021:05 | Titans | NFL | 8 |
| 2022-10-30 21:25:0030.10.2022 | Colts | 21:25:0021:25 | Washington | NFL | 8 |
| 2022-10-30 21:25:0030.10.2022 | Rams | 21:25:0021:25 | 49ers | NFL | 8 |
| 2022-10-30 21:25:0030.10.2022 | Seahawks | 21:25:0021:25 | Giants | NFL | 8 |
| 2022-10-31 01:20:0031.10.2022 | Bills | 01:20:001:20 | Packers | NFL | 8 |
| 2022-11-01 01:15:0001.11.2022 | Browns | 01:15:001:15 | Bengals | NFL | 8 |
| 2022-11-04 01:15:0004.11.2022 | Texans | 01:15:001:15 | Eagles | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Falcons | 19:00:0019:00 | Chargers | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Bears | 19:00:0019:00 | Dolphins | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Bengals | 19:00:0019:00 | Panthers | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Lions | 19:00:0019:00 | Packers | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Jaguars | 19:00:0019:00 | Raiders | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Patriots | 19:00:0019:00 | Colts | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Jets | 19:00:0019:00 | Bills | NFL | 9 |
| 2022-11-06 19:00:0006.11.2022 | Washington | 19:00:0019:00 | Vikings | NFL | 9 |
| 2022-11-06 22:05:0006.11.2022 | Arizona Cardinals | 22:05:0022:05 | Seahawks | NFL | 9 |
| 2022-11-06 22:25:0006.11.2022 | Buccaneers | 22:25:0022:25 | Rams | NFL | 9 |
| 2022-11-07 02:20:0007.11.2022 | Chiefs | 02:20:002:20 | Titans | NFL | 9 |
| 2022-11-08 02:15:0008.11.2022 | Saints | 02:15:002:15 | Ravens | NFL | 9 |
| 2022-11-11 02:15:0011.11.2022 | Panthers | 02:15:002:15 | Falcons | NFL | 10 |
| 2022-11-13 15:30:0013.11.2022 | Buccaneers | 15:30:0015:30 | Seahawks | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Bills | 19:00:0019:00 | Vikings | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Bears | 19:00:0019:00 | Lions | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Chiefs | 19:00:0019:00 | Jaguars | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Dolphins | 19:00:0019:00 | Browns | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Giants | 19:00:0019:00 | Texans | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Steelers | 19:00:0019:00 | Saints | NFL | 10 |
| 2022-11-13 19:00:0013.11.2022 | Titans | 19:00:0019:00 | Broncos | NFL | 10 |
| 2022-11-13 22:05:0013.11.2022 | Raiders | 22:05:0022:05 | Colts | NFL | 10 |
| 2022-11-13 22:25:0013.11.2022 | Packers | 22:25:0022:25 | Cowboys | NFL | 10 |
| 2022-11-13 22:25:0013.11.2022 | Rams | 22:25:0022:25 | Arizona Cardinals | NFL | 10 |
| 2022-11-14 02:20:0014.11.2022 | 49ers | 02:20:002:20 | Chargers | NFL | 10 |
| 2022-11-15 02:15:0015.11.2022 | Eagles | 02:15:002:15 | Washington | NFL | 10 |
| 2022-11-18 02:15:0018.11.2022 | Packers | 02:15:002:15 | Titans | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Falcons | 19:00:0019:00 | Bears | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Ravens | 19:00:0019:00 | Panthers | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Bills | 19:00:0019:00 | Browns | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Texans | 19:00:0019:00 | Washington | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Colts | 19:00:0019:00 | Eagles | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Patriots | 19:00:0019:00 | Jets | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Saints | 19:00:0019:00 | Rams | NFL | 11 |
| 2022-11-20 19:00:0020.11.2022 | Giants | 19:00:0019:00 | Lions | NFL | 11 |
| 2022-11-20 22:05:0020.11.2022 | Broncos | 22:05:0022:05 | Raiders | NFL | 11 |
| 2022-11-20 22:25:0020.11.2022 | Chargers | 22:25:0022:25 | Chiefs | NFL | 11 |
| 2022-11-20 22:25:0020.11.2022 | Vikings | 22:25:0022:25 | Cowboys | NFL | 11 |
| 2022-11-21 02:20:0021.11.2022 | Steelers | 02:20:002:20 | Bengals | NFL | 11 |
| 2022-11-22 01:15:0022.11.2022 | Arizona Cardinals | 01:15:001:15 | 49ers | NFL | 11 |
| 2022-11-24 18:30:0024.11.2022 | Lions | 18:30:0018:30 | Bills | NFL | 12 |
| 2022-11-24 22:30:0024.11.2022 | Cowboys | 22:30:0022:30 | Giants | NFL | 12 |
| 2022-11-25 02:20:0025.11.2022 | Vikings | 02:20:002:20 | Patriots | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Panthers | 19:00:0019:00 | Broncos | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Browns | 19:00:0019:00 | Buccaneers | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Jaguars | 19:00:0019:00 | Ravens | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Dolphins | 19:00:0019:00 | Texans | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Jets | 19:00:0019:00 | Bears | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Titans | 19:00:0019:00 | Bengals | NFL | 12 |
| 2022-11-27 19:00:0027.11.2022 | Washington | 19:00:0019:00 | Falcons | NFL | 12 |
| 2022-11-27 22:05:0027.11.2022 | Arizona Cardinals | 22:05:0022:05 | Chargers | NFL | 12 |
| 2022-11-27 22:05:0027.11.2022 | Seahawks | 22:05:0022:05 | Raiders | NFL | 12 |
| 2022-11-27 22:25:0027.11.2022 | Chiefs | 22:25:0022:25 | Rams | NFL | 12 |
| 2022-11-27 22:25:0027.11.2022 | 49ers | 22:25:0022:25 | Saints | NFL | 12 |
| 2022-11-28 02:20:0028.11.2022 | Eagles | 02:20:002:20 | Packers | NFL | 12 |
| 2022-11-29 02:15:0029.11.2022 | Colts | 02:15:002:15 | Steelers | NFL | 12 |
| 2022-12-02 02:15:0002.12.2022 | Patriots | 02:15:002:15 | Bills | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Falcons | 19:00:0019:00 | Steelers | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Ravens | 19:00:0019:00 | Broncos | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Bears | 19:00:0019:00 | Packers | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Lions | 19:00:0019:00 | Jaguars | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Texans | 19:00:0019:00 | Browns | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Vikings | 19:00:0019:00 | Jets | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Giants | 19:00:0019:00 | Washington | NFL | 13 |
| 2022-12-04 19:00:0004.12.2022 | Eagles | 19:00:0019:00 | Titans | NFL | 13 |
| 2022-12-04 22:05:0004.12.2022 | Rams | 22:05:0022:05 | Seahawks | NFL | 13 |
| 2022-12-04 22:05:0004.12.2022 | 49ers | 22:05:0022:05 | Dolphins | NFL | 13 |
| 2022-12-04 22:25:0004.12.2022 | Bengals | 22:25:0022:25 | Chiefs | NFL | 13 |
| 2022-12-04 22:25:0004.12.2022 | Raiders | 22:25:0022:25 | Chargers | NFL | 13 |
| 2022-12-05 02:20:0005.12.2022 | Cowboys | 02:20:002:20 | Colts | NFL | 13 |
| 2022-12-06 02:15:0006.12.2022 | Buccaneers | 02:15:002:15 | Saints | NFL | 13 |
| 2022-12-09 02:15:0009.12.2022 | Rams | 02:15:002:15 | Raiders | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Bills | 19:00:0019:00 | Jets | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Bengals | 19:00:0019:00 | Browns | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Cowboys | 19:00:0019:00 | Texans | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Lions | 19:00:0019:00 | Vikings | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Giants | 19:00:0019:00 | Eagles | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Steelers | 19:00:0019:00 | Ravens | NFL | 14 |
| 2022-12-11 19:00:0011.12.2022 | Titans | 19:00:0019:00 | Jaguars | NFL | 14 |
| 2022-12-11 22:05:0011.12.2022 | Chargers | 22:05:0022:05 | Dolphins | NFL | 14 |
| 2022-12-11 22:25:0011.12.2022 | 49ers | 22:25:0022:25 | Buccaneers | NFL | 14 |
| 2022-12-11 22:25:0011.12.2022 | Seahawks | 22:25:0022:25 | Panthers | NFL | 14 |
| 2022-12-12 02:20:0012.12.2022 | Broncos | 02:20:002:20 | Chiefs | NFL | 14 |
| 2022-12-13 02:15:0013.12.2022 | Arizona Cardinals | 02:15:002:15 | Patriots | NFL | 14 |
| 2022-12-16 02:15:0016.12.2022 | Seahawks | 02:15:002:15 | 49ers | NFL | 15 |
| 2022-12-18 00:00:0018.12.2022 | Bills | 00:00:000:00 | Dolphins | NFL | 15 |
| 2022-12-18 00:00:0018.12.2022 | Browns | 00:00:000:00 | Ravens | NFL | 15 |
| 2022-12-18 00:00:0018.12.2022 | Vikings | 00:00:000:00 | Colts | NFL | 15 |
| 2022-12-18 00:00:0018.12.2022 | Saints | 00:00:000:00 | Falcons | NFL | 15 |
| 2022-12-18 00:00:0018.12.2022 | Washington | 00:00:000:00 | Giants | NFL | 15 |
| 2022-12-18 19:00:0018.12.2022 | Panthers | 19:00:0019:00 | Steelers | NFL | 15 |
| 2022-12-18 19:00:0018.12.2022 | Bears | 19:00:0019:00 | Eagles | NFL | 15 |
| 2022-12-18 19:00:0018.12.2022 | Texans | 19:00:0019:00 | Chiefs | NFL | 15 |
| 2022-12-18 19:00:0018.12.2022 | Jaguars | 19:00:0019:00 | Cowboys | NFL | 15 |
| 2022-12-18 19:00:0018.12.2022 | Jets | 19:00:0019:00 | Lions | NFL | 15 |
| 2022-12-18 22:05:0018.12.2022 | Broncos | 22:05:0022:05 | Arizona Cardinals | NFL | 15 |
| 2022-12-18 22:25:0018.12.2022 | Chargers | 22:25:0022:25 | Titans | NFL | 15 |
| 2022-12-18 22:25:0018.12.2022 | Buccaneers | 22:25:0022:25 | Bengals | NFL | 15 |
| 2022-12-19 02:20:0019.12.2022 | Raiders | 02:20:002:20 | Patriots | NFL | 15 |
| 2022-12-20 02:15:0020.12.2022 | Packers | 02:15:002:15 | Rams | NFL | 15 |
| 2022-12-23 02:15:0023.12.2022 | Jets | 02:15:002:15 | Jaguars | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Ravens | 19:00:0019:00 | Falcons | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Panthers | 19:00:0019:00 | Lions | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Bears | 19:00:0019:00 | Bills | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Browns | 19:00:0019:00 | Saints | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Chiefs | 19:00:0019:00 | Seahawks | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Vikings | 19:00:0019:00 | Giants | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Patriots | 19:00:0019:00 | Bengals | NFL | 16 |
| 2022-12-24 19:00:0024.12.2022 | Titans | 19:00:0019:00 | Texans | NFL | 16 |
| 2022-12-24 22:05:0024.12.2022 | 49ers | 22:05:0022:05 | Washington | NFL | 16 |
| 2022-12-24 22:25:0024.12.2022 | Cowboys | 22:25:0022:25 | Eagles | NFL | 16 |
| 2022-12-25 02:15:0025.12.2022 | Steelers | 02:15:002:15 | Raiders | NFL | 16 |
| 2022-12-25 19:00:0025.12.2022 | Dolphins | 19:00:0019:00 | Packers | NFL | 16 |
| 2022-12-25 22:30:0025.12.2022 | Rams | 22:30:0022:30 | Broncos | NFL | 16 |
| 2022-12-26 02:20:0026.12.2022 | Arizona Cardinals | 02:20:002:20 | Buccaneers | NFL | 16 |
| 2022-12-27 02:15:0027.12.2022 | Colts | 02:15:002:15 | Chargers | NFL | 16 |
| 2022-12-30 02:15:0030.12.2022 | Titans | 02:15:002:15 | Cowboys | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Falcons | 19:00:0019:00 | Arizona Cardinals | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Ravens | 19:00:0019:00 | Steelers | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Lions | 19:00:0019:00 | Bears | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Texans | 19:00:0019:00 | Jaguars | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Chiefs | 19:00:0019:00 | Broncos | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Patriots | 19:00:0019:00 | Dolphins | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Giants | 19:00:0019:00 | Colts | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Eagles | 19:00:0019:00 | Saints | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Buccaneers | 19:00:0019:00 | Panthers | NFL | 17 |
| 2023-01-01 19:00:0001.01.2023 | Washington | 19:00:0019:00 | Browns | NFL | 17 |
| 2023-01-01 22:05:0001.01.2023 | Raiders | 22:05:0022:05 | 49ers | NFL | 17 |
| 2023-01-01 22:05:0001.01.2023 | Seahawks | 22:05:0022:05 | Jets | NFL | 17 |
| 2023-01-01 22:25:0001.01.2023 | Packers | 22:25:0022:25 | Vikings | NFL | 17 |
| 2023-01-02 02:20:0002.01.2023 | Chargers | 02:20:002:20 | Rams | NFL | 17 |
| 2023-01-03 02:30:0003.01.2023 | Bengals | 02:30:002:30 | Bills | NFL | 17 |
| 2023-01-08 00:00:0008.01.2023 | Falcons | 00:00:000:00 | Buccaneers | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Bills | 00:00:000:00 | Patriots | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Bears | 00:00:000:00 | Vikings | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Bengals | 00:00:000:00 | Ravens | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Broncos | 00:00:000:00 | Chargers | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Packers | 00:00:000:00 | Lions | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Colts | 00:00:000:00 | Texans | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Jaguars | 00:00:000:00 | Titans | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Raiders | 00:00:000:00 | Chiefs | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Dolphins | 00:00:000:00 | Jets | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Saints | 00:00:000:00 | Panthers | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Eagles | 00:00:000:00 | Giants | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Steelers | 00:00:000:00 | Browns | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | 49ers | 00:00:000:00 | Arizona Cardinals | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Seahawks | 00:00:000:00 | Rams | NFL | 18 |
| 2023-01-08 00:00:0008.01.2023 | Washington | 00:00:000:00 | Cowboys | NFL | 18 |
