| 2022-03-26 18:00:0026.03.2022 | Winterthur Warriors | 6 – 34 | Bern Grizzlies | N/A |
| 2022-03-27 14:30:0027.03.2022 | Geneva Seahawks | 13 – 0 | Zurich Renegades | N/A |
| 2022-04-03 14:30:0003.04.2022 | Calanda Broncos | 49 – 21 | Thun Tigers | N/A |
| 2022-04-10 14:30:0010.04.2022 | Bern Grizzlies | 27 – 0 | Geneva Seahawks | N/A |
| 2022-04-10 14:30:0010.04.2022 | Thun Tigers | 35 – 20 | Winterthur Warriors | N/A |
| 2022-04-10 14:30:0010.04.2022 | Basel Gladiators | 15 – 34 | Calanda Broncos | N/A |
| 2022-04-16 18:00:0016.04.2022 | Basel Gladiators | 3 – 31 | Bern Grizzlies | N/A |
| 2022-04-18 14:30:0018.04.2022 | Calanda Broncos | 34 – 6 | Winterthur Warriors | N/A |
| 2022-04-18 14:30:0018.04.2022 | Thun Tigers | 34 – 0 | Zurich Renegades | N/A |
| 2022-04-24 14:30:0024.04.2022 | Bern Grizzlies | 24 – 7 | Thun Tigers | N/A |
| 2022-04-24 14:30:0024.04.2022 | Geneva Seahawks | 0 – 21 | Calanda Broncos | N/A |
| 2022-04-30 18:00:0030.04.2022 | Winterthur Warriors | 22 – 14 | Zurich Renegades | N/A |
| 2022-05-01 14:30:0001.05.2022 | Bern Grizzlies | 27 – 20 | Calanda Broncos | N/A |
| 2022-05-01 14:30:0001.05.2022 | Thun Tigers | 41 – 6 | Geneva Seahawks | N/A |
| 2022-05-07 18:00:0007.05.2022 | Calanda Broncos | 35 – 6 | Basel Gladiators | N/A |
| 2022-05-08 14:30:0008.05.2022 | Zurich Renegades | 19 – 62 | Thun Tigers | N/A |
| 2022-05-08 15:30:0008.05.2022 | Geneva Seahawks | 21 – 7 | Winterthur Warriors | N/A |
| 2022-05-15 14:30:0015.05.2022 | Zurich Renegades | 0 – 40 | Basel Gladiators | N/A |
| 2022-05-21 18:00:0021.05.2022 | Basel Gladiators | 24 – 7 | Geneva Seahawks | N/A |
| 2022-05-22 14:30:0022.05.2022 | Bern Grizzlies | 69 – 7 | Winterthur Warriors | N/A |
| 2022-05-22 14:30:0022.05.2022 | Zurich Renegades | 20 – 44 | Calanda Broncos | N/A |
| 2022-05-28 18:00:0028.05.2022 | Calanda Broncos | 21 – 14 | Geneva Seahawks | N/A |
| 2022-05-28 18:00:0028.05.2022 | Thun Tigers | 20 – 24 | Basel Gladiators | N/A |
| 2022-05-29 14:30:0029.05.2022 | Zurich Renegades | 12 – 38 | Winterthur Warriors | N/A |
| 2022-06-04 18:00:0004.06.2022 | Geneva Seahawks | 0 – 55 | Bern Grizzlies | N/A |
| 2022-06-04 18:00:0004.06.2022 | Winterthur Warriors | 21 – 24 | Thun Tigers | N/A |
| 2022-06-04 18:00:0004.06.2022 | Basel Gladiators | 28 – 15 | Zurich Renegades | N/A |
| 2022-06-11 18:00:0011.06.2022 | Calanda Broncos | 23 – 30 | Bern Grizzlies | N/A |
| 2022-06-11 18:00:0011.06.2022 | Winterthur Warriors | 13 – 21 | Basel Gladiators | N/A |
| 2022-06-12 14:30:0012.06.2022 | Zurich Renegades | 37 – 6 | Geneva Seahawks | N/A |
| 2022-06-18 18:00:0018.06.2022 | Geneva Seahawks | 3 – 14 | Basel Gladiators | N/A |
| 2022-06-18 18:00:0018.06.2022 | Winterthur Warriors | 27 – 28 | Calanda Broncos | N/A |
| 2022-06-19 14:00:0019.06.2022 | Thun Tigers | 6 – 36 | Bern Grizzlies | N/A |
| 2022-06-26 14:00:0026.06.2022 | Bern Grizzlies | 35 – 0 | Zurich Renegades | N/A |
| 2022-06-26 18:00:0026.06.2022 | Basel Gladiators | 34 – 6 | Thun Tigers | N/A |
Bern Grizzlies
Calanda Broncos
Basel Gladiators
Thun Tigers
Winterthur Warriors
Geneva Seahawks
Zurich Renegades