| 2022-03-26 14:30:0026.03.2022 | Winterthur Warriors | 14 – 6 | Argovia Pirates | N/A |
| 2022-03-27 11:00:0027.03.2022 | Geneva Seahawks | 30 – 12 | Bern Grizzlies | N/A |
| 2022-04-03 11:00:0003.04.2022 | Calanda Broncos | 59 – 22 | Basel Gladiators | N/A |
| 2022-04-10 11:00:0010.04.2022 | Basel Gladiators | 35 – 44 | Argovia Pirates | N/A |
| 2022-04-10 11:00:0010.04.2022 | Bern Grizzlies | 8 – 25 | Zurich Renegades | N/A |
| 2022-04-10 11:00:0010.04.2022 | St. Gallen Bears | 7 – 44 | Geneva Seahawks | N/A |
| 2022-04-10 11:00:0010.04.2022 | Thun Tigers | 48 – 8 | Winterthur Warriors | N/A |
| 2022-04-16 14:30:0016.04.2022 | Basel Gladiators | 14 – 30 | Geneva Seahawks | N/A |
| 2022-04-18 11:00:0018.04.2022 | Calanda Broncos | 57 – 12 | Winterthur Warriors | N/A |
| 2022-04-18 11:00:0018.04.2022 | St. Gallen Bears | 7 – 60 | Zurich Renegades | N/A |
| 2022-04-18 11:00:0018.04.2022 | Thun Tigers | 52 – 7 | Argovia Pirates | N/A |
| 2022-04-24 11:00:0024.04.2022 | Bern Grizzlies | 18 – 20 | Winterthur Warriors | N/A |
| 2022-04-24 11:00:0024.04.2022 | Geneva Seahawks | 36 – 22 | Zurich Renegades | N/A |
| 2022-04-24 11:00:0024.04.2022 | St. Gallen Bears | 0 – 53 | Calanda Broncos | N/A |
| 2022-04-30 14:30:0030.04.2022 | Argovia Pirates | 14 – 36 | Geneva Seahawks | N/A |
| 2022-04-30 14:30:0030.04.2022 | Winterthur Warriors | 12 – 39 | Basel Gladiators | N/A |
| 2022-05-01 11:00:0001.05.2022 | Bern Grizzlies | 33 – 12 | St. Gallen Bears | N/A |
| 2022-05-01 11:00:0001.05.2022 | Thun Tigers | 39 – 43 | Calanda Broncos | N/A |
| 2022-05-07 14:30:0007.05.2022 | Calanda Broncos | 36 – 0 | Bern Grizzlies | N/A |
| 2022-05-07 14:30:0007.05.2022 | St. Gallen Bears | 6 – 58 | Thun Tigers | N/A |
| 2022-05-08 11:00:0008.05.2022 | Zurich Renegades | 20 – 27 | Basel Gladiators | N/A |
| 2022-05-08 12:00:0008.05.2022 | Geneva Seahawks | 50 – 0 | Winterthur Warriors | N/A |
| 2022-05-14 14:30:0014.05.2022 | Argovia Pirates | 15 – 0 | Bern Grizzlies | N/A |
| 2022-05-15 11:00:0015.05.2022 | Zurich Renegades | 24 – 33 | Thun Tigers | N/A |
| 2022-05-21 14:30:0021.05.2022 | Basel Gladiators | 52 – 7 | St. Gallen Bears | N/A |
| 2022-05-22 11:00:0022.05.2022 | Bern Grizzlies | 6 – 41 | Thun Tigers | N/A |
| 2022-05-22 11:00:0022.05.2022 | Zurich Renegades | 23 – 15 | Calanda Broncos | N/A |
| 2022-05-28 14:30:0028.05.2022 | Calanda Broncos | 47 – 26 | Geneva Seahawks | N/A |
| 2022-05-28 14:30:0028.05.2022 | Thun Tigers | 42 – 21 | Basel Gladiators | N/A |
| 2022-05-28 14:30:0028.05.2022 | Winterthur Warriors | 34 – 14 | St. Gallen Bears | N/A |
| 2022-05-29 11:00:0029.05.2022 | Zurich Renegades | 33 – 8 | Argovia Pirates | N/A |
| 2022-06-04 14:30:0004.06.2022 | Argovia Pirates | 12 – 44 | Calanda Broncos | N/A |
| 2022-06-04 14:30:0004.06.2022 | Basel Gladiators | 27 – 8 | Bern Grizzlies | N/A |
| 2022-06-04 14:30:0004.06.2022 | Geneva Seahawks | 32 – 44 | Thun Tigers | N/A |
| 2022-06-04 14:30:0004.06.2022 | Winterthur Warriors | 26 – 43 | Zurich Renegades | N/A |
| 2022-06-11 14:30:0011.06.2022 | Argovia Pirates | 8 – 23 | St. Gallen Bears | N/A |
Calanda Broncos
Thun Tigers
Geneva Seahawks
Zurich Renegades
Basel Gladiators
Winterthur Warriors
Argovia Pirates
Bern Grizzlies
St. Gallen Bears