| 2021-05-29 15:00:0029.05.2021 | Bern Grizzlies vs Bienna Jets | 42 – 43 |
| 2021-05-29 18:00:0029.05.2021 | Calanda Broncos vs St. Gallen Bears | 21 – 20 |
| 2021-05-30 11:00:0030.05.2021 | Gladiators vs Tigers | 35 – 20 |
| 2021-06-05 15:00:0005.06.2021 | Winterthur Warriors vs Thun Tigers | 7 – 14 |
| 2021-06-06 11:00:0006.06.2021 | Zurich Renegades vs Bern Grizzlies | 35 – 20 |
| 2021-06-06 12:00:0006.06.2021 | Geneva Seahawks vs St. Gallen Bears | 46 – 14 |
| 2021-06-13 11:00:0013.06.2021 | Zurich Renegades vs St. Gallen Bears | 32 – 3 |
| 2021-06-13 14:00:0013.06.2021 | Bienna Jets vs Winterthur Warriors | 6 – 32 |
| 2021-06-13 14:00:0013.06.2021 | Thun Tigers vs Geneva Seahawks | 19 – 14 |
| 2021-06-20 11:00:0020.06.2021 | Basel Gladiators vs Winterthur Warriors | 28 – 8 |
| 2021-06-20 11:00:0020.06.2021 | Calanda Broncos vs Bienna Jets | 42 – 20 |
| 2021-06-20 11:00:0020.06.2021 | St. Gallen Bears vs Bern Grizzlies | 28 – 44 |
| 2021-06-20 14:00:0020.06.2021 | Thun Tigers vs Zurich Renegades | 14 – 23 |
| 2021-07-03 15:00:0003.07.2021 | Bern Grizzlies vs Basel Gladiators | 20 – 13 |
| 2021-07-03 15:00:0003.07.2021 | Calanda Broncos vs Zurich Renegades | 30 – 7 |
| 2021-07-04 11:00:0004.07.2021 | Geneva Seahawks vs Bienna Jets | 34 – 21 |
| 2021-07-04 11:00:0004.07.2021 | Thun Tigers vs St. Gallen Bears | 28 – 3 |
| 2021-07-10 15:00:0010.07.2021 | Bienna Jets vs Thun Tigers | 21 – 26 |
| 2021-07-11 11:00:0011.07.2021 | Bern Grizzlies vs Calanda Broncos | 8 – 41 |
| 2021-07-11 11:00:0011.07.2021 | Geneva Seahawks vs Basel Gladiators | 22 – 27 |
| 2021-07-11 11:00:0011.07.2021 | Zurich Renegades vs Winterthur Warriors | 23 – 0 |
| 2021-07-17 15:00:0017.07.2021 | Basel Gladiators vs Calanda Broncos | 7 – 16 |
| 2021-07-17 15:00:0017.07.2021 | Winterthur Warriors vs Geneva Seahawks | 32 – 6 |
| 2021-08-14 15:00:0014.08.2021 | Winterthur Warriors vs Calanda Broncos | 12 – 23 |
| 2021-08-15 11:00:0015.08.2021 | Bienna Jets vs Basel Gladiators | 14 – 46 |
| 2021-08-22 11:00:0022.08.2021 | Thun Tigers vs Bern Grizzlies | 41 – 14 |
| 2021-08-22 14:00:0022.08.2021 | Zurich Renegades vs Geneva Seahawks | 6 – 0 |
| 2021-08-28 15:00:0028.08.2021 | Winterthur Warriors vs Bern Grizzlies | 18 – 46 |
| 2021-08-29 11:00:0029.08.2021 | Bienna Jets vs Zurich Renegades | 0 – 50 |
| 2021-08-29 11:00:0029.08.2021 | St. Gallen Bears vs Basel Gladiators | 0 – 49 |
| 2021-08-29 12:00:0029.08.2021 | Geneva Seahawks vs Calanda Broncos | 8 – 27 |
| 2021-09-02 14:00:5002.09.2021 | Juniorbowl 2021: Calanda Broncos vs Basel Gladiators | 14:00:5014:00 |
| 2021-09-04 15:00:0004.09.2021 | Calanda Broncos vs Thun Tigers | 30 – 25 |
| 2021-09-05 11:00:0005.09.2021 | Bern Grizzlies vs Geneva Seahawks | 40 – 38 |
| 2021-09-05 11:00:0005.09.2021 | Basel Gladiators vs Zurich Renegades | 21 – 32 |
| 2021-09-05 11:00:0005.09.2021 | St. Gallen Bears vs Winterthur Warriors | 14 – 27 |
| 2021-09-12 11:00:0012.09.2021 | St. Gallen Bears vs Bienna Jets | 50 – 0 |
| 2021-09-18 18:00:2418.09.2021 | U19 Wild Card: Tigers vs Grizzlies | 20 – 40 |
| 2021-09-18 18:00:5318.09.2021 | U19 Wild Card: Gladiators vs Warriors | 35 – 21 |
| 2021-09-25 15:00:5525.09.2021 | U19 Semifinal: Calanda Broncos vs Bern Grizzlies | 25 – 8 |
| 2021-09-26 11:00:3626.09.2021 | U19 Semifinal: Zurich Renegades vs Basel Gladiators | 14 – 24 |
| 2021-10-02 14:00:3402.10.2021 | Juniorbowl: Calanda Broncos vs Basel Gladiators | 21 – 6 |
